Evidence map›Paper›PMID 36119210›Full record

ArticleJournal of family medicine and primary care2022

A systematic review of mucormycosis cases in COVID-19: Is it an unholy trilogy of COVID-19, diabetes mellitus, and corticosteroids?

Rajesh Kumar, Arup Kumar Misra, Siddhartha Dutta, Ajay Gupta, Bharat Kumar, Jaykaran Charan

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mucormycosis in COVID-19 patients: A cross-sectional study at IGIMS, Patna.Journal of family medicine and primary care · 2023
    Article
  8. Article
  9. Article
  10. A fatal case of disseminated pulmonary and renal mucormycosis caused by Rhizopus microspores.Revista do Instituto de Medicina Tropical de Sao Paulo · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rajesh KumarDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Patna, Bihar, India.
Arup Kumar MisraDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Mangalagiri, Andhra Pradesh, India.
Siddhartha DuttaDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Rajkot, Gujarat, India.
Ajay GuptaDepartment of Pharmacology, Pt. Jawahar Lal Nehru Government Medical College and Hospital, Chamba, Himachal Pradesh, India.
Bharat KumarDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.
Jaykaran CharanDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.
All India Institute of Medical Sciences · INAll India Institute of Medical Sciences Jodhpur · INGovernment Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A significant surge of cases of mucormycosis is seen in individuals with COVID-19 with presence of diabetes mellitus (DM) and usage of corticosteroids. We aim to conduct a systematic analysis of the cases involving presence of mucormycosis and to find out its association with COVID-19, diabetes mellitus, and corticosteroids. Method: The electronic records of PubMed, Google Scholar, and Science Direct were searched for the case reports and case series that reported mucormycosis in association of COVID-19. The particulars of each case report and case series were retrieved, stored and analyzed. Results: In this study, 476 cases of mucormycosis were reported. In 346 cases of mucormycosis, the patients were found to be COVID-19 positive. The incidence of diabetes Mellitus (DM) was 67.01%. Corticosteroid was administered in 57.77% of the cases. Mortality was reported in 36.34% of the cases. Conclusion: An immunosuppressive environment created due to the COVID-19, diabetes mellitus, and extensive use of corticosteroid provide a suitable background for the increased incidence of mucormycosis. The COVID task force should adopt an aggressive multidisciplinary approach to optimize the use of corticosteroids and maintain glucose in the optimal range.

Indexed as

CorticosteroidsCOVID-19diabetes mellitusmucormycosisSARS-CoV-2

Identifiers

PMID36119210
PMCPMC9480822
OpenAlexW4285111779

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.