Evidence map›Paper›PMID 36119201›Full record

ArticleJournal of family medicine and primary care2022

Drug utilization study of antiepileptic drugs in the pediatric department, tertiary care hospital, Bangalore, India.

Zahra Khoshdel, Shibi Tomas, Marziye Jafari

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zahra KhoshdelDepartment of Pharmacy Practice, Karnataka College of Pharmacy, Bengaluru, Karnataka, India.
Shibi TomasDepartment of Pharmacy Practice, Karnataka College of Pharmacy, Bengaluru, Karnataka, India.
Marziye JafariDepartment of Clinical Pharmacy, Faculty of Pharmacy, Guilan University of Medical Science, Rasht, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The main objective of the present study is to find out the loose links between prescription of medication and its utilization in the pediatric department, especially with drugs that belong to the antiepileptic medication category. Methodology: This prospective observational study was carried out for 6 months in the Department of Pharmacy Practice, Tertiary Care Hospital, Bangalore. The study was conducted on 100 patients receiving antiepileptic medication. The patient demographics and all medically relevant information were noted in a predefined data collection form. Results: The study showed that the maximum number of patients receiving antiepileptic medication belongs to the age group of 2-6 years. While comparing the prevalence of ADR levetiracetam, phenytoin and clobazam were identified which are associated with ADR. The highly prescribed drug was valproic acid and carbamazepine. The ADRs documented were loss of appetite, vomiting, anemia, and Steven-Johnson syndrome. Evaluation of prescription was performed, which is a major factor in drug-related ADRs. In the discussion part, various methods of improvement in the prevention of ADRs due to prescription error have been suggested which can improve drug utilization and precaution. An economic study was done in the end to put a light on the cost-effective treatment therapy which might improve patient adherence. Conclusion: It was concluded that valproic acid was a highly prescribed drug and carbamazepine was the second-most prescribed drug. It was found that majority of prescription was without a generic name and with inappropriate abbreviations.

Indexed as

Antiepileptic drugsdrug utilizationepilepsypediatricprescription

Identifiers

PMID36119201
PMCPMC9480813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.