Evidence map›Paper›PMID 36119137›Full record

ArticleJournal of ophthalmology2022

Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study.

Marian Kiel, Stephanie D Grabitz, Susanne Hopf, Thomas Koeck, Philipp S Wild, Irene Schmidtmann, Karl J Lackner, Thomas Münzel, Manfred E Beutel, Norbert Pfeiffer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Marian KielDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0002-7841-804X
Stephanie D GrabitzDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Susanne HopfDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Thomas KoeckPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Philipp S WildPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Irene SchmidtmannInstitute for Medical Biostatistics Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Karl J LacknerInstitute for Clinical Chemistry and Laboratory Medicine, University Medicine of the Johannes Gutenberg University Mainz, Mainz, Germany.
Thomas MünzelGerman Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.
Manfred E BeutelDepartment for Psychosomatic Medicine und Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Alexander K SchusterDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Results: 18,335 eyes of 9,559 participants aged 40 to 80 years were included in the analysis. Median pupil diameter was 4.19 mm in right eyes and 4.12 mm in left eyes. A smaller pupil was associated with older age, hyperopic refractive error, previous cataract surgery, diabetes, obesity, and ACE inhibitor intake, whereas wider pupil was associated with female gender, arterial hypertension, intake of tricyclic antidepressants, and intake of SNRI and tetracyclic antidepressants. Socioeconomic status and smoking were not associated with pupil size. Conclusion: Individuals of older age, after cataract surgery, under therapy with ACE inhibitors and with diabetes have a smaller pupil. This should be taken into account when planning nonmydriatic fundus photography-based screening programs, for instance, for diabetic retinopathy.

Identifiers

PMID36119137
PMCPMC9481399
OpenAlexW4295138548

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.