ArticleFrontiers in immunology2022
Host inflammatory response is the major factor in the progression of
Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Development and validation of an interpretable machine learning model using routine laboratory biomarkers to stratify severe pneumonia risk in young children.Journal of advanced research · 2026Article
- Article
- Development and internal validation of a TLR2-based nomogram for diagnosing pulmonary infection in type 2 diabetes.Frontiers in endocrinology · 2026Article
- Incidence, clinical characteristics, and risk factors of acute kidney injury in patients withFrontiers in cellular and infection microbiology · 2026Article
- Clinical Features and Risk Factors for Rhabdomyolysis in Patients withInfection and drug resistance · 2026Article
- Systemic inflammation, multi-organ injury, and acute kidney risk in psittacosis pneumonia: a biomarker-driven clinical characterization.Frontiers in cellular and infection microbiology · 2026Article
- Chlamydia psittacosis infection complicating cerebral infarction: A case report and literature review.Medicine · 2025Review
- Psittacosis pneumonia with the reversed halo sign: a case report and literature review.BMC infectious diseases · 2025Review
- Liver Function Abnormalities in Patients withInfection and drug resistance · 2025Article
- Clinical characteristics ofFrontiers in medicine · 2025Article
- Multiple infections secondary to immunosuppression after Chlamydia psittaci infection: a case report.BMC infectious diseases · 2024Article
- Psittacosis Pneumonia Features, Distinguishing Characteristics, and Outcomes: A Retrospective Study.Infection and drug resistance · 2024Article
- Article
- Case report: A clinical case study of six patients withFrontiers in cellular and infection microbiology · 2023Article
- Clinical features and risk factors of liver injury in patients withFrontiers in cellular and infection microbiology · 2023Article
- Article
- Article
- Clinical identification and microbiota analysis ofFrontiers in cellular and infection microbiology · 2023Article
- Evaluation of Protective Immune Responses Induced in BALB/c Mice and Goats by theAnimals : an open access journal from MDPI · 2022Article
- The silencing of SAAL1 suppresses pneumonia progression via modulating the NLR signaling pathway.Annals of translational medicine · 2022Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Methods: To clarify the host inflammatory response in psittacosis, we analyzed clinical parameters, and compared transcriptomic data, concentrations of plasma cytokines/chemokines, and changes of immune cell populations in 17 laboratory-confirmed psittacosis cases, namely, 8 pneumonia and 9 bronchitis individuals, in order to assess transcriptomic profiles and pro-inflammatory responses. Results: Psittacosis cases with pneumonia were found to have abnormal routine blood indices, liver damage, and unilateral pulmonary high-attenuation consolidation. Transcriptome sequencing revealed markedly elevated expression of several pro-inflammatory genes, especially interleukins and chemokines. A multiplex-biometric immunoassay showed that pneumonia cases had higher levels of serum cytokines (G-CSF, IL-2, IL-6, IL-10, IL-18, IP-10, MCP-3, and TNF-α) than bronchitis cases. Increases in activated neutrophils and decreases in the number of lymphocytes were also observed in pneumonia cases. Conclusion: We identified a number of plasma biomarkers distinct to
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