Evidence map›Paper›PMID 36118827›Full record

ArticleComputational and mathematical methods in medicine2022

MicroRNA-1306-5p Regulates the METTL14-Guided m6A Methylation to Repress Acute Myeloid Leukemia.

Jiajia Li, Yanping Wu, Meng Wang, Xiaofeng Chen, Zhongyu Li, Xue Bai, Haotian Wu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Targeting intracellular mRNA mJournal of advanced research · 2026
    Review
  2. Review
  3. Small molecule inhibitors targeting mJournal of hematology & oncology · 2024
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiajia LiDepartment of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.ORCID https://orcid.org/0000-0003-4694-0789
Yanping WuDepartment of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Meng WangDepartment of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Xiaofeng ChenDepartment of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Zhongyu LiDepartment of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Xue BaiDepartment of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Haotian WuBengbu Medical College, Bengbu, Anhui, China.
First Affiliated Hospital of Bengbu Medical College · CNBengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

miRNA and m6A methylation are two key regulators in cancers. However, in acute myeloid leukemia (AML), the relationship of miRNA and m6A methylation remains unclear. The present work is aimed at determining the effect of m6A methylation induced by miRNAs on AML and its underlying mechanism. The expression of METTL14 was detected by qRT-PCR and western blot. The growth of HL-60 cells was analyzed by CCK-8, Transwell assay, and flow cytometry. Tumor-bearing mice were established, and Ki-67 staining assay was used to detect the proliferation

Indexed as

Leukemia, Myeloid, AcuteAnimalsCell Line, TumorCell ProliferationKi-67 AntigenMethylationMethyltransferasesMiceMicroRNAsKi-67 AntigenMethyltransferasesMETTL14 protein, humanMicroRNAsMIRN1306 microRNA, human

Identifiers

PMID36118827
PMCPMC9473907
OpenAlexW4296001844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.