Evidence map›Paper›PMID 36118773›Full record

ArticleFrontiers in nutrition2022

Efficacy of a vegetal mixture composed of

Laura Micheli, Alessandra Toti, Elena Lucarini, Valentina Ferrara, Clara Ciampi, Guendalina Olivero, Anna Pittaluga, Luisa Mattoli, Caroline Pelucchini, Michela Burico and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Laura MicheliNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Alessandra TotiNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Elena LucariniNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Valentina FerraraNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Clara CiampiNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Guendalina OliveroDepartment of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genoa, Genoa, Italy.
Anna PittalugaDepartment of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genoa, Genoa, Italy.
Luisa MattoliInnovation and Medical Science Division, Aboca SpA Società Agricola, Sansepolcro, Italy.
Caroline PelucchiniInnovation and Medical Science Division, Aboca SpA Società Agricola, Sansepolcro, Italy.
Michela BuricoInnovation and Medical Science Division, Aboca SpA Società Agricola, Sansepolcro, Italy.
Jacopo LucciInnovation and Medical Science Division, Aboca SpA Società Agricola, Sansepolcro, Italy.
Donatello CarrinoAnatomy and Histology Section, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Alessandra PaciniAnatomy and Histology Section, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Stefano PallantiPsychiatry Section, Department of Neurofarba, University of Florence, Florence, Italy.
Lorenzo Di Cesare MannelliNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Carla GhelardiniNeurofarba-Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
University of Florence · ITAboca (Italy) · ITUniversity of Genoa · ITAlbert Einstein College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental evidence suggests that neuroinflammation is a key pathological event of many diseases affecting the nervous system. It has been well recognized that these devastating illnesses (e.g., Alzheimer's, Parkinson's, depression, and chronic pain) are multifactorial, involving many pathogenic mechanisms, reason why pharmacological treatments are unsatisfactory. The purpose of this study was to evaluate the efficacy of a vegetal mixture capable of offering a multiple approach required to manage the multifactoriality of neuroinflammation. A mixture composed of

Indexed as

CNS complement proteinsglial cellsLPSmood disordersneuroinflammationpainvegetal mixture

Identifiers

PMID36118773
PMCPMC9472218
OpenAlexW4293740512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.