Evidence map›Paper›PMID 36118758›Full record

ArticleFrontiers in nutrition2022

Association between caloric adequacy and short-term clinical outcomes in critically ill patients using a weight-based equation: Secondary analysis of a cluster-randomized controlled trial.

Cheng Lv, Xingwei Jiang, Yi Long, Zirui Liu, Jiajia Lin, Cuili Wu, Xianghong Ye, Ruiling Ye, Yuxiu Liu, Man Liu and 7 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The effect of blended tube feeding compared to conventional formula on clinical outcomes in adults: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2026
    Pooled it
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Cheng LvDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Xingwei JiangDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Southeast University, Nanjing, China.
Yi LongDepartment of Critical Care Medicine, Chongqing University Cancer Hospital, Chongqing, China.
Zirui LiuDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Jiajia LinDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Cuili WuDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Xianghong YeDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Ruiling YeDepartment of Critical Care Medicine, Chongqing University Cancer Hospital, Chongqing, China.
Yuxiu LiuDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Man LiuDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Yang LiuDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Wensong ChenDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Lin GaoDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Zhihui TongDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Lu KeDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Zhengying JiangDepartment of Critical Care Medicine, Chongqing University Cancer Hospital, Chongqing, China.
Weiqin LiDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is controversy over the optimal energy delivery in intensive care units (ICUs). In this study, we aimed to evaluate the association between different caloric adequacy assessed by a weight-based equation and short-term clinical outcomes in a cohort of critically ill patients. Methods: This is a secondary analysis of a cluster-randomized controlled trial ( Results: A total of 1,694 patients were included. Compared with normocaloric feeding, hypocaloric feeding significantly increased the risk of 28-day mortality (hazard ratio [ Conclusion: Energy delivery below 70% of the estimated energy requirement during days 3-7 of critical illness is associated with 28-day mortality. Clinical trial registration: [https://www.isrctn.com/ISRCTN12233792], identifier [ISRCTN12233792].

Indexed as

critical illnessenergy intakehypocaloric feedingmortalityresting energy expenditure

Identifiers

PMID36118758
PMCPMC9478102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.