ArticleFrontiers in aging neuroscience2022
White matter hyperintensities in Burning Mouth Syndrome assessed according to the Age-Related White Matter Changes scale.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- A systematic review of brain health in adults with chronic pain.Anaesthesia · 2026Pooled it
- Morpho-Histo-Cytological Evaluation of Oral Tissues in Burning Mouth Syndrome: A Systematic Review.Journal of oral rehabilitation · 2025Pooled it
- Small Fiber Neuropathy in Burning Mouth Syndrome: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Orofacial pain and dementia: a brief narrative review of associations, putative mechanisms, and relevant clinical considerations.Odontology · 2026Review
- Uncovering Frailty in Burning Mouth Syndrome: Insights From a SUNFRAIL+ Based Multidimensional Assessment.Journal of oral rehabilitation · 2026Article
- Beyond Oral Pain: A Unique Case of Burning Mouth Syndrome With Coexisting Vulvodynia and Cognitive Impairment in a Postmenopausal Woman.Clinical case reports · 2026Article
- Dose-response and recovery trajectories of fall prevention rehabilitation in older patients with vertigo: a retrospective cohort study based on vestibular and gait impairment phenotypes.Frontiers in neurology · 2026Article
- Burning mouth syndrome: updates on pathogenesis and diagnostic algorithms.Journal of oral & facial pain and headache · 2025Review
- Eighty-Four-Month Clinical Outcomes of Autologous Dentin Graft Using Tooth TransformerJournal of functional biomaterials · 2025Article
- Evaluation of the Possible Correlation Between Dental Occlusion and Craniomandibular Disorders by Means of TeethanJournal of clinical medicine · 2025Article
- Cognitive profile in burning mouth syndrome versus mild cognitive impairment: A comparative study.Oral diseases · 2025Article
- Does orthodontic postgraduate education influence the choice of orthodontic treatment?Frontiers in dental medicine · 2025Article
- Gender differences in pain perception among burning mouth syndrome patients: a cross-sectional study of 242 men and 242 women.Scientific reports · 2024Article
- Trends of burning mouth syndrome: a bibliometric study.Frontiers in neurology · 2024Review
- Non-Communicable Diseases and Associated Risk Factors in Burning Mouth Syndrome Patients.Medicina (Kaunas, Lithuania) · 2023Article
- Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients.Journal of clinical medicine · 2023Article
- Article
- Burning Mouth Syndrome and Hypertension: Prevalence, Gender Differences and Association with Pain and Psycho-Social Characteristics-A Case Control Study.International journal of environmental research and public health · 2023Article
- Editorial: Chronic pain in neuropsychiatric diseases.Frontiers in human neuroscience · 2023Article
- Burning Mouth Syndrome: An Overview and Future Perspectives.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: White matter hyperintensities (WMHs) of the brain are observed in normal aging, in various subtypes of dementia and in chronic pain, playing a crucial role in pain processing. The aim of the study has been to assess the WMHs in Burning Mouth Syndrome (BMS) patients by means of the Age-Related White Matter Changes scale (ARWMCs) and to analyze their predictors. Methods: One hundred BMS patients were prospectively recruited and underwent magnetic resonance imaging (MRI) of the brain. Their ARWMCs scores were compared with those of an equal number of healthy subjects matched for age and sex. Intensity and quality of pain, psychological profile, and blood biomarkers of BMS patients were further investigated to find potential predictors of WMHs. Specifically, the Numeric Rating Scale (NRS), Short-Form McGill Pain Questionnaire (SF-MPQ), Hamilton rating scale for Depression and Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) were administered. Results: The BMS patients presented statistically significant higher scores on the ARWMCs compared to the controls, especially in the right frontal, left frontal, right parietal-occipital, left parietal-occipital, right temporal and left temporal lobes ( Conclusion: Patients with BMS showed a higher frequency of WMHs of the brain as suggested by the higher ARWCs scores compared with the normal aging of the healthy subjects. These findings could have a role in the pathophysiology of the disease and potentially affect and enhance pain perception.
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