Evidence map›Paper›PMID 36118374›Full record

ArticleDrug, healthcare and patient safety2022

Opioid Utilization and Management in the Setting of Stewardship During Inpatient Rehab Care.

Laura Murphy, Kori Leblanc, Souzi Badr, Emily Ching, Lynda Mao, Naomi Steenhof, Bassem Hamandi, Bonita Rubin, Ada Seto, Andrea D Furlan

Abstract read
In one paragraph

Article in Drug, healthcare and patient safety, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Changes in opioid prescribing and high-risk co-prescribing after implementation of the 2016 CDC opioid guideline among older adults with and without cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura MurphyDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.ORCID 0000-0002-4787-8879
Kori LeblancDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.ORCID 0000-0002-9996-0663
Souzi BadrDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Emily ChingDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Lynda MaoDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Naomi SteenhofDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Bassem HamandiDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Bonita RubinDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Ada SetoDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Andrea D FurlanKITE Research Institute, University Health Network, Toronto, ON, Canada.ORCID 0000-0001-6138-8510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Opioid utilization and management in an inpatient rehabilitation setting have not been widely described, despite the unique opportunities that exist in this setting to support opioid stewardship across transitions in care. We aimed to characterize opioid utilization and management by interprofessional teams across a large, inpatient rehabilitation setting after incorporation of opioid stewardship principles by pharmacists as part of their daily practice. Patients and methods: This was a retrospective chart review at Toronto Rehab, University Health Network, Toronto, Canada. Patients with admission orders for any opioid from November 2017 to February 2018 were included. Complex continuing care and palliative care patients were excluded. Descriptive statistics were primarily used to describe the data as well as univariate linear regression to compare associations with milligram morphine equivalent (MME) reduction. Results: A total of 448 patients were included. A reduction in total daily MME was seen in 49% (n=219) of the patients during their inpatient stay, with 73% (n=159) of these patients having a reduction of ≥50%. Sixty-nine percent (n=311) of the patients received an opioid prescription at discharge, with most scheduled (90%, n=98) with a supply of less than 30 days. Rehabilitation length of stay was correlated with a MME decrease during rehab (p<0.01), suggesting that longer lengths of stay contributed to a greater reduction in MME. Patients with chronic opioid use prior to acute care admission (p=0.01), and those who started extended-release opioids during acute care (p=0.02) were significantly less likely to discontinue opioids during rehab stay. Conclusion: Opioid utilization and management in the setting of opioid stewardship across inpatient rehab and transitions of care were characterized. Opportunities exist for further quality improvement initiatives within inpatient rehabilitation and acute care settings to identify and support patients with complex pain management needs.

Indexed as

discharge prescriptionmedication reconciliationmedication safetyopioidpain managementpharmacy practice

Identifiers

PMID36118374
PMCPMC9477087

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.