Evidence map›Paper›PMID 36118077›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Jujuboside A Exhibits an Antiepileptogenic Effect in the Rat Model via Protection against Traumatic Epilepsy-Induced Oxidative Stress and Inflammatory Responses.

Wei Lu, Zhangze Wu, Chong Zhang, Tingting Gao, Xiaoyang Ling, Min Xu, Wenhua Wang, Xuegang Jin, Keran Li, Long Chen and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Wei LuDepartment of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Kunshan, China.
Zhangze WuDepartment of Neurosurgery, Air Force Hospital of Eastern Theater, Nanjing University of Chinese Medicine, Nanjing, China.
Chong ZhangThe First Retired Cadres' Sanatorium of Jiangsu Military Region, Nanjing, China.
Tingting GaoDepartment of Neurosurgery, Air Force Hospital of Eastern Theater, Nanjing University of Chinese Medicine, Nanjing, China.
Xiaoyang LingDepartment of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Kunshan, China.
Min XuDepartment of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Kunshan, China.
Wenhua WangDepartment of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Kunshan, China.
Xuegang JinDepartment of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Kunshan, China.
Keran LiFaculty of Life Science, School of Biomedical Science, University of Bristol, Bristol, UK.
Long ChenDepartment of Neurosurgery, Kunshan Hospital of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Kunshan, China.ORCID https://orcid.org/0000-0002-2170-8556
Jinjuan WangDepartment of Pharmacy, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-7039-9756
Zhongyang SunDepartment of Orthopedics, Air Force Hospital of Eastern Theater, Nanjing University of Chinese Medicine, Nanjing, China.ORCID https://orcid.org/0000-0002-6558-2174
Nanjing University of Chinese Medicine · CNNanjing General Hospital of Nanjing Military Command · CNNanjing Medical University · CNUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injuries (TBI) are the greatest source of death in trauma, and post-traumatic epilepsy (PTE) is one of the common complications of TBI. Oxidative stress and inflammatory responses play an important role in the process of PTE. Many studies have shown that Jujuboside A has powerful antioxidant and anti-inflammatory properties. However, it is not known whether Jujuboside A has an anti-epileptic effect. The influences of Jujuboside A in the experimental FeCl

Identifiers

PMID36118077
PMCPMC9481365
OpenAlexW4296259931

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.