Evidence map›Paper›PMID 36118048›Full record

ArticleParasite epidemiology and control2022

Chemical composition, antileishmanial, and cytotoxic effects

Hossein Mahmoudvand, Javad Ghasemian Yadegari, Amal Khudair Khalaf, Mohammad Javad Hashemi, Setareh Dastyarhaghighi, Iraj Salimikia

Open access · goldAbstract read
In one paragraph

Article in Parasite epidemiology and control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Essential Oil ofPlants (Basel, Switzerland) · 2026
    Review
  5. Potential activity ofFrontiers in pharmacology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. In vitro Evaluation of the Potent Antileishmanial Activity ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Javad Ghasemian YadegariDepartment of Pharmacognosy, Lorestan University of Medical Sciences, Khorramabad, Iran.
Amal Khudair KhalafDepartment of Microbiology, College of Medicine, University of Thiqar, Iraq.
Mohammad Javad HashemiStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Setareh DastyarhaghighiStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Iraj SalimikiaDepartment of Pharmacognosy, Lorestan University of Medical Sciences, Khorramabad, Iran.
Lorestan University of Medical Sciences · IRThi Qar University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The current study was aimed to evaluate the chemical composition, as well as antileishmanial and cytotoxic effects of the essential oil of Methods: The chemical composition of the essential oil was analyzed by a gas chromatograph connected to a mass spectrometer (GC/MS). The MTT (3-(4.5-dimethylthiazol-2-yl) - 2.5-diphenyl tetrazolium bromide) assay was used to study the effects of the essential oil and terpinolene against promastigotes while the macrophage model was used for evaluating the effect of Results: The main compounds were terpinolene (77.72%), n-nonanal (4.47%), and linalool (4.35%), respectively. The 50% inhibitory concentrations (IC Conclusion: The results of the present study indicated that

Indexed as

AmastigoteLeishmaniasisMTTNitric oxidePromastigote

Identifiers

PMID36118048
PMCPMC9475300
OpenAlexW4294739329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.