Evidence map›Paper›PMID 36118041›Full record

ReviewFrontiers in cellular and infection microbiology2022

Implications of m6A methylation and microbiota interaction in non-small cell lung cancer: From basics to therapeutics.

Fen-Sheng Qiu, Jia-Qi He, Yu-Sen Zhong, Mei-Ying Guo, Chen-Huan Yu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. The Role and Diagnostic Efficacy of the METTL14/GADD45B mCellular and molecular neurobiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. The Emerging Role of METTL3 in Lung Diseases.International journal of molecular sciences · 2025
    Review
  6. Journal of thoracic disease · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. FTO in Lung Cancer: Its Progression and Therapeutic Potential.Combinatorial chemistry & high throughput screening · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Silencing of mAmerican journal of cancer research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Fen-Sheng QiuKey Laboratory of Experimental Animal and Safety Evaluation, Zhejiang Academy of Medical Sciences (Hangzhou Medical College), Hangzhou, China.
Jia-Qi HePharmaceutical Department, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Yu-Sen ZhongKey Laboratory of Experimental Animal and Safety Evaluation, Zhejiang Academy of Medical Sciences (Hangzhou Medical College), Hangzhou, China.
Mei-Ying GuoKey Laboratory of Experimental Animal and Safety Evaluation, Zhejiang Academy of Medical Sciences (Hangzhou Medical College), Hangzhou, China.
Chen-Huan YuKey Laboratory of Experimental Animal and Safety Evaluation, Zhejiang Academy of Medical Sciences (Hangzhou Medical College), Hangzhou, China.
Hangzhou Medical College · CNUniversity of Chinese Academy of Sciences · CNZhejiang Academy of Medical Sciences · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyladenine (m6A) is one of the most common RNA epigenetic modifications in all higher eukaryotes. Increasing evidence demonstrated that m6A-related proteins, acted as oncogenes or tumor suppressors, are abnormally expressed in the cell lines and tissues of non-small cell lung cancer (NSCLC). In addition, lung as the special immune organ contacts with the outer environments and thereby inevitably suffers from different types of microbial pathogen attack. Those microbial pathogens affect the development, progression, and clinical outcomes of NSCLC

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMicrobiotaAdenosineHumansMethylationRNAAdenosineRNAbiomarkerepigeneticsFTOinhibitorm6AMETTL3

Identifiers

PMID36118041
PMCPMC9478539
OpenAlexW4294190083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.