Evidence map›Paper›PMID 36118031›Full record

ArticleFrontiers in cellular and infection microbiology2022

Acquisition of resistance to ceftazidime-avibactam during infection treatment in

Patricia García, Bárbara Brito, Manuel Alcalde-Rico, José M Munita, Jose R W Martínez, Jorge Olivares-Pacheco, Valeria Quiroz, Aniela Wozniak

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Heterogeneous multicopy of blaNature communications · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Patricia GarcíaLaboratory of Microbiology, Department of Clinical Laboratories, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Bárbara BritoAustralian Institute for Microbiology & Infection, Faculty of Science, University of Technology, Sydney, Australia.
Manuel Alcalde-RicoMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.
José M MunitaMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.
Jose R W MartínezMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.
Jorge Olivares-PachecoMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.
Valeria QuirozLaboratory of Microbiology, Department of Clinical Laboratories, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Aniela WozniakLaboratory of Microbiology, Department of Clinical Laboratories, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Universidad del Desarrollo · CLClínica Alemana · CLMillennium Initiative for Collaborative Research on Bacterial Resistance · CLPontificia Universidad Católica de Valparaíso · CLUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftazidime/Avibactam (CAZ/AVI) is frequently used to treat KPC-producing

Indexed as

CeftazidimePseudomonas aeruginosaAnti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesCarbapenemsDrug CombinationsHumansMicrobial Sensitivity TestsMutationPorinsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo Compoundsbeta-LactamasesCarbapenemsCeftazidimeDrug CombinationsPorinsblaKPC-2 geneceftazidime/avibactam resistanceD179Y substitutionpseudomonas aeruginosaTn4401b transposon

Identifiers

PMID36118031
PMCPMC9478442
OpenAlexW4294204073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.