Evidence map›Paper›PMID 36118016›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2022

Timing of Organ Procurement From Brain-Dead Donors Associates With Short- and Long-Term Outcomes After Liver Transplantation.

Verner Eerola, Ilkka Helanterä, Fredrik Åberg, Marko Lempinen, Heikki Mäkisalo, Arno Nordin, Helena Isoniemi, Ville Sallinen

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Association of Procurement Time With Pancreas Transplant Outcomes in Brain-Dead Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Verner EerolaDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Ilkka HelanteräDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Fredrik ÅbergDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Marko LempinenDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Heikki MäkisaloDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Arno NordinDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Helena IsoniemiDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
Ville SallinenDepartment of Transplantation and Liver Surgery, Helsinki University Hospital and the University of Helsinki, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FIVarsinais-Suomen Sairaanhoitopiiri · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain death-induced cytokine storm is thought to harm transplantable organs. However, longer procurement times have been associated with non-inferior or better outcomes in kidney, heart, and lung transplants, while optimal procurement time for liver allografts is unknown. Our aim was to analyze the association of time interval from brain death to organ procurement with liver allograft outcomes in two nationwide cohorts. The association of procurement interval with graft survival and short-term complications was analysed in multivariable models. Altogether 643 and 58,017 orthotopic liver transplantations from brain-dead donors were included from Finland between June 2004 and December 2017 and the US between January 2008 and August 2018, respectively. Median time from brain death to organ procurement was 10.5 h in Finland and 34.6 h in the US. Longer interval associated with better graft survival (non-linearly,

Indexed as

End Stage Liver DiseaseLiver TransplantationTissue and Organ ProcurementBrainBrain DeathHumansSeverity of Illness Indexbrain deathdonor hepatectomygraft survivalliver allograft functionliver transplant dysfunctionorgan allocationprocurement surgery

Identifiers

PMID36118016
PMCPMC9472133
OpenAlexW4293742321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.