Evidence map›Paper›PMID 36117923›Full record

ArticleDiabetology international2022

Serum ketone body measurement in patients with diabetic ketoacidosis.

Tomonao Hirobata, Hidefumi Inaba, Yosuke Kaido, Daisuke Kosugi, Saya Itoh, Takaaki Matsuoka, Gen Inoue

Open access · greenAbstract read
In one paragraph

Article in Diabetology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tomonao HirobataDepartment of Diabetes and Endocrinology, Japanese Red Cross Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558 Japan.
Hidefumi InabaDepartment of Diabetes and Endocrinology, Japanese Red Cross Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558 Japan.ORCID 0000-0002-7718-734X
Yosuke KaidoDepartment of Diabetes and Endocrinology, Japanese Red Cross Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558 Japan.
Daisuke KosugiDepartment of Diabetes and Endocrinology, Japanese Red Cross Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558 Japan.
Saya ItohDepartment of Diabetes and Endocrinology, Japanese Red Cross Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558 Japan.
Takaaki MatsuokaThe First Department of Medicine, Wakayama Medical University, Hospital, 811-1 Kimiidera, Wakayama, Wakayama 641-8509 Japan.
Gen InoueDepartment of Diabetes and Endocrinology, Japanese Red Cross Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558 Japan.
Japanese Red Cross Society Wakayama Medical Center · JPWakayama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic ketoacidosis (DKA) is a critical manifestation in patients with diabetes mellitus. DKA has been conventionally diagnosed by the presence of hyperglycemia (blood glucose levels > 250 mg/dl) and metabolic acidosis (blood gas bicarbonate [HCO Methods: We have retrospectively evaluated patients with hyperglycemia whose serum ketone body levels at the outpatient clinic and emergency department were measured simultaneously with blood gas analysis during 2011-2019. Clinical backgrounds, severity of diabetes, serum ketone bodies, and blood gas factors were analyzed. Results: Seventy-two patients were enrolled in the study, after the exclusion of patients who had ketosis due to factors other than diabetes. Serum ketone body levels were negatively correlated with the levels of blood HCO Conclusions: Serum ketone body levels were thought to be useful in the diagnosis of DKA. Further investigations with increased numbers of patients are required to establish the appropriate application of serum ketone bodies in patients with DKA. Supplementary Information: The online version contains supplementary material available at 10.1007/s13340-022-00581-2.

Indexed as

Diabetic ketoacidosisKetone bodiesType 1 diabetes mellitusType 2 diabetes mellitus

Identifiers

PMID36117923
PMCPMC9478004
OpenAlexW4223943577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.