Evidence map›Paper›PMID 36117854›Full record

ArticleIBRO neuroscience reports2022

Changes in spontaneous and odorant-induced single-unit activity of mitral/tufted neurons of the rat olfactory bulb during xylazine-tiletamine-zolazepam anesthesia.

V N Kiroy, P O Kosenko, A B Smolikov, A I Saevskiy, E V Aslanyan, P D Shaposhnikov, Yu A Rebrov, F V Arsenyev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IBRO neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

V N KiroySouthern Federal University, Rostov-on-Don, Russia.
P O KosenkoSouthern Federal University, Rostov-on-Don, Russia.
A B SmolikovSouthern Federal University, Rostov-on-Don, Russia.
A I SaevskiySouthern Federal University, Rostov-on-Don, Russia.
E V AslanyanSouthern Federal University, Rostov-on-Don, Russia.
P D ShaposhnikovSouthern Federal University, Rostov-on-Don, Russia.
Yu A RebrovSouthern Federal University, Rostov-on-Don, Russia.
F V ArsenyevFoundation for Advanced Research of Russia, Russia.
Southern Federal University · RURussian Foundation for Basic Research · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nature and severity of mitral/tufted (M/T) cells reactions to odorants presented in anesthesia depend on various factors, and, above all, the nature and concentration of the odor, anesthesia, and the functional state of the olfactory bulb (OB). Compared to wakefulness, under anesthesia, the intensity of OB M/T cells responses to the odorants presented increases. However, the influence of anesthesia dynamics on the intensity of such responses has not been studied. To address this problem in rats, the activity of M/T cells and the local field potentials (LFP) in OB were recorded in the course of xylazine-tiletamine-zolazepam (XTZ) anesthesia. It has been shown that in the course of the anesthesia, the average frequency of background and odorant-induced single-unit activity of M/T cells increases, while the dominant frequency value of LFP in the gamma frequency range (90-170 Hz), on the contrary, decreases. The observed effects are assumed to be associated with changes in the functional state of the OB and systems for processing olfactory information in anesthesia.

Indexed as

Gamma activityLFP, local field potentialMitral/tufted cellsOB, olfactory bulbRat olfactory bulbXTZ, xylazine-tiletamine-zolazepamXylazine-tiletamine-zolazepam anesthesiaМ/Т, mitral/tufted cells

Identifiers

PMID36117854
PMCPMC9474852
OpenAlexW4294959581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.