ReviewFrontiers in surgery2022
Impact of early Kasai portoenterostomy on short-term outcomes of biliary atresia: A systematic review and meta-analysis.
Review in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Serum predictors of native liver survival post-Kasai: Systematic review and meta-analysis.Journal of pediatric gastroenterology and nutrition · 2026Pooled it
- The diagnostic performance of ultrasound features for biliary atresia: a systematic review and updated meta-analysis.Pediatric surgery international · 2025Pooled it
- Long-Term Outcomes of Living Donor Liver Transplantation in Children With Alagille Syndrome: Results From Vanguard Multicenter Study of International Living Donor Liver Transplantation Group.Pediatric transplantation · 2026Trial
- Development and validation of a nomogram for predicting the clearance of jaundice in children with biliary Atresia after Kasai portoenterostomy.Langenbeck's archives of surgery · 2025Trial
- Analysis of factors influencing the timing of Kasai portoenterostomy in biliary atresia and the impact of early surgery on prognosis.Pediatric surgery international · 2026Article
- Biliary Atresia With Situs Inversus Abdominalis Managed by Kasai Portoenterostomy: A Case Report From Muhimbili National Hospital, Tanzania.Clinical case reports · 2026Article
- The Italian biliary atresia registry: Insights and lessons from the retrospective analysis of a 10-year period cohort.Journal of pediatric gastroenterology and nutrition · 2026Article
- Successful surgical intervention and management of biliary atresia in a 4-month-old infant: a case report.International journal of surgery case reports · 2026Article
- Standardised Transplant-Orientated Kasai Portoenterostomy in a Combined Kasai and Transplant Programme: An 11-Year Single-Surgeon Series of 74 Consecutive Cases.Journal of clinical medicine · 2026Article
- A nomogram for predicting early- and mid-term native liver survival after surgery in patients with type III biliary atresia: a single-center retrospective study.BMC surgery · 2026Article
- Upregulated beta-defensin-1 in murine and human biliary atresia associates with human native liver survival.Scientific reports · 2026Article
- Pediatric Cholestasis: A Practical Approach to Histological Diagnosis.Diagnostics (Basel, Switzerland) · 2026Review
- Short-Term Outcome of Infants with Biliary Artesia Following Kasai Portoenterostomy.Indian journal of pediatrics · 2026Article
- Development of a nomogram for predicting 2-year native liver survival in biliary atresia using dynamic liver function indicators.Frontiers in pediatrics · 2026Article
- Effects of multimodal analgesia with combined quadratus lumborum block on enhanced recovery after Kasai portoenterostomy in infants with biliary atresia: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Late Referral of Biliary Atresia and Poor Clinical Outcomes.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Observational
- Primary antibiotic prophylaxis in biliary atresia did not demonstrate decreased infection rate: Multi-centre retrospective study.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- A comparative study of portoenterostomy and choledochojejunostomy in New Zealand rabbits under immunosuppression.Frontiers in surgery · 2025Article
- Laparoscopic Kasai portoenterostomy for biliary atresia: first experience from Central Asia.Frontiers in pediatrics · 2025Article
- Kasai procedure or liver transplantation: how should we choose in biliary atresia?Hepatobiliary surgery and nutrition · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Good outcomes of biliary atresia (BA) are conventionally achieved after early Kasai portoenterostomy (KP). However, in some recent pieces of literature, there are discrepancies in the influence of age in Kasai procedure on postoperative short-term prognosis. This meta-analysis aims to evaluate the effects of earlier KP on short-term surgical prognosis of BA and clarify these discrepancies in recent studies. Methods: To identify related studies, PubMed, Embase, Web of Science, Cochrane, and the Chinese National Knowledge Infrastructure database were searched up to March 2022. Data for the impact of age at KP on clinical prognosis were extracted, including jaundice clearance rate (JCR) and native liver survival rate (NLSR). Results: A total of 14 articles were included in the present study, which involve a total of 3,276 patients with BA who underwent Kasai procedure. Compared with patients older than 91 days of age, patients 90 days of age or younger exhibited significantly better JCR [odds ratio (OR), 3.05; 95% confidence interval (CI), 2.23-4.17; Conclusion: A significantly better short-term JCR and NLSRs were achieved among patients with BA treated using a KP procedure at ≤90 days of age compared with those treated at >90 days of age. There was no further improvement in the short-term JCR when the procedure was performed at ≤60 days compared with those treated at 61-90 days of age. However, treatment at ≤60 days of age was associated with a significant improvement in NLSR. Therefore, the timing of KP does exert an important effect on short-term clinical outcomes of patients with BA.
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