ReviewChinese herbal medicines2021
How to identify "Material basis-Quality markers" more accurately in Chinese herbal medicines from modern chromatography-mass spectrometry data-sets: Opportunities and challenges of chemometric tools.
Review in Chinese herbal medicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Screening and Validation of Q-Markers for Daodi Authenticity ofMolecules (Basel, Switzerland) · 2026Article
- Unveiling bioactive components inChinese herbal medicines · 2025Article
- Mass spectrometry-based metabolomic as a powerful tool to unravel the component and mechanism in TCM.Chinese medicine · 2025Review
- Target Cell Extraction and Spectrum-Effect Relationship Coupled with BP Neural Network Classification for Screening Potential Bioactive Components in Ginseng Extract with a Protective Effect against Myocardial Damage.Molecules (Basel, Switzerland) · 2024Article
- Analysis of GC × GC fingerprints from medicinal materials using a novel contour detection algorithm: A case ofJournal of pharmaceutical analysis · 2024Article
- A comprehensive investigation on the chemical changes of traditional Chinese medicine with classic processing technology: Polygonum multiflorum under nine cycles of steaming and sunning as a case study.Analytical and bioanalytical chemistry · 2024Article
- Gain deeper insights into traditional Chinese medicines using multidimensional chromatography combined with chemometric approaches.Chinese herbal medicines · 2024Review
- Analysis of Quality Differences in Radix Dipsaci before and after Processing with Salt Based on Quantitative Control of HPLC Multi-Indicator Components Combined with Chemometrics.International journal of analytical chemistry · 2024Article
- Three-tiered authentication of herbal traditional Chinese medicine ingredients used in women's health provides progressive qualitative and quantitative insight.Frontiers in pharmacology · 2024Article
- Recent trends of machine learning applied to multi-source data of medicinal plants.Journal of pharmaceutical analysis · 2023Review
- Machine learning applications for multi-source data of edible crops: A review of current trends and future prospects.Food chemistry: X · 2023Review
- Phytochemical analysis, antioxidant, α-glucosidase inhibitory activity, and toxicity evaluation of Orthosiphon stamineus leaf extract.Scientific reports · 2023Article
- Article
- Identification of anti-inflammatory components inChinese herbal medicines · 2023Article
- Integrating Enhanced Profiling and Chemometrics to Unveil the Potential Markers for Differentiating among the Leaves ofMolecules (Basel, Switzerland) · 2022Article
- Predicting for anti-(mutant) SARS-CoV-2 and anti-inflammation compounds of Lianhua Qingwen Capsules in treating COVID-19.Chinese medicine · 2022Article
- Connotation and scientific research points of processing of Mongolian medicinal materials.Chinese herbal medicines · 2022Review
- Early Warning of Ischemic Stroke Based on Atherosclerosis Index Combined With Serum Markers.The Journal of clinical endocrinology and metabolism · 2022Article
- Systematic Qualitative and Quantitative Analyses of Wenxin Granule via Ultra-High Performance Liquid Chromatography Coupled with Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry and Triple Quadrupole-Linear Ion Trap Mass Spectrometry.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern chromatography - mass spectrometer (MS) technology is an essential weapon in the exploration of traditional Chinese medicines (TCMs) which is based on the "effectiveness-material basis-quality markers (Q-markers)". Nevertheless, the hardware bottleneck and irregular operation will limit the accuracy and comprehensiveness of test results. Chemometrics was thereby used to solve the existing problems: 1) The method of 'design-modeling-optimization' can be adopted to solve the multi-factor and multi-level problems in sample preparation/ parameter setting; 2) The approaches of signal processing can be used to calibrate the deviation from retention time (rt) dimension and mass-to-charge ratio (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.