Evidence map›Paper›PMID 36117726›Full record

ArticleStem cells international2022

Correlation Analysis between Chronic Osteomyelitis and Bacterial Biofilm.

Kai Huang, Bingyuan Lin, Yiyang Liu, Haiyong Ren, Qiaofeng Guo

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Stem cells international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Understanding bacterial biofilms: From definition to treatment strategies.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  2. Suppression ofIranian journal of basic medical sciences · 2024
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

  • Retraction · 2024-01-24Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Paper Mill · Computer-Aided Content or Computer-Generated Content · Unreliable Results and/or Conclusions · · See also: https://pubpeer.com/publications/AFE8B259D1A46612B459714B1751F1
  • Retracted
5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kai HuangDepartment of Orthopedics, Tongde Hospital of Zhejiang Province, China.ORCID https://orcid.org/0000-0002-3932-6636
Bingyuan LinDepartment of Orthopedics, Tongde Hospital of Zhejiang Province, China.ORCID https://orcid.org/0000-0001-9267-2661
Yiyang LiuDepartment of Orthopedics, Tongde Hospital of Zhejiang Province, China.ORCID https://orcid.org/0000-0002-2356-8294
Haiyong RenDepartment of Orthopedics, Tongde Hospital of Zhejiang Province, China.ORCID https://orcid.org/0000-0002-1779-8990
Qiaofeng GuoDepartment of Orthopedics, Tongde Hospital of Zhejiang Province, China.ORCID https://orcid.org/0000-0002-9491-9768
Tongde Hospital of Zhejiang Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study the role of bacterial biofilm (BBF) in the formation of chronic osteomyelitis and its prevention and treatment. Methods: In this paper, a large amount of relevant literature was searched for analysis and summary, and the key words "chronic osteomyelitis," "bacterial biofilm," "infection," and "debridement" were searched in databases, mainly CNKI, Wanfang, and Wipu. The search was conducted until December 2020. The role of bacterial biofilm formation in chronic osteomyelitis and its prevention were analyzed. Results: Chronic osteomyelitis is formed mainly due to poor blood supply and drug-resistant bacteria, of which cellular biofilm is the most important cause. BBF forms on the surface of necrotic soft tissue and bone tissue, which has a protective effect on bacteria and greatly enhances their resistance to antibiotics, leading to difficulties in complete bacterial clearance and recurrent infections in osteomyelitis. Conclusion: Through an in-depth study of the molecular biology and signal transduction of osteomyelitis biofilm, antibiotic biofilm treatment strategies and surgical debridement remain the focus of clinical translation of chronic osteomyelitis.

Identifiers

PMID36117726
PMCPMC9477593
OpenAlexW4295096203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.