Evidence map›Paper›PMID 36117693›Full record

ArticleFrontiers in physiology2022

Involvement of transmembrane protein 184a during angiogenesis in zebrafish embryos.

Cassandra J Field, Alexis M Perez, Taryn Samet, Victoria Ricles, M Kathryn Iovine, Linda J Lowe-Krentz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cassandra J FieldDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
Alexis M PerezDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
Taryn SametDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
Victoria RiclesDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
M Kathryn IovineDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
Linda J Lowe-KrentzDepartment of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
Lehigh University · US

Funding

PUTATIVE HEPARIN RECEPTOR IN SMOOTH MUSCLE CELLSR15HL054269 · NHLBI · LEHIGH UNIVERSITY · PI LOWE-KRENTZ, LINDA J · 1995 to 2022
$2.2M
NHLBI NIH HHS R15 HL054269
6 · The paper itself

Abstract

Angiogenesis, the outgrowth of new blood vessels from existing vasculature, is critical during development, tissue formation, and wound healing. In response to vascular endothelial growth factors (VEGFs), endothelial cells are activated to proliferate and move towards the signal, extending the vessel. These events are directed by VEGF-VEGF receptor (Vegfr2) signal transduction, which in turn is modulated by heparan sulfate proteoglycans (HSPGs). HSPGs are glycoproteins covalently attached to HS glycosaminoglycan chains. Transmembrane protein 184a (Tmem184a) has been recently identified as a heparin receptor, which is believed to bind heparan sulfate chains

Indexed as

angiogenesisheparan-binding proteinheparan sulfate proteoglycansTMEM184Avascular endothelial growth factor

Identifiers

PMID36117693
PMCPMC9478037
OpenAlexW4294176379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.