ArticleFrontiers in neuroscience2022
Binary acoustic metasurfaces for dynamic focusing of transcranial ultrasound.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- High-Frequency Ultrasound Focusing Using Low-Cost PMMA and PDMS Acoustic Lenses.Micromachines · 2026Article
- Design and Structure of a Non-Coaxial Multi-Focal Composite Fresnel Acoustic Lens for Synergistic Ultrasound Stimulation of Multiple Brain Regions.Sensors (Basel, Switzerland) · 2025Article
- The role of focused ultrasound for pediatric brain tumors: current insights and future implications on treatment strategies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- Airy-beam holographic sonogenetics for advancing neuromodulation precision and flexibility.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Phase-Optimized Multi-Step Phase Acoustic Metasurfaces for Arbitrary Multifocal Beamforming.Micromachines · 2023Article
- Advanced Temporally-Spatially Precise Technologies for On-Demand Neurological Disorder Intervention.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial focused ultrasound (tFUS) is a promising technique for non-invasive and spatially targeted neuromodulation and treatment of brain diseases. Acoustic lenses were designed to correct the skull-induced beam aberration, but these designs could only generate static focused ultrasound beams inside the brain. Here, we designed and 3D printed binary acoustic metasurfaces (BAMs) for skull aberration correction and dynamic ultrasound beam focusing. BAMs were designed by binarizing the phase distribution at the surface of the metasurfaces. The phase distribution was calculated based on time reversal to correct the skull-induced phase aberration. The binarization enabled the ultrasound beam to be dynamically steered along wave propagation direction by adjusting the operation frequency of the incident ultrasound wave. The designed BAMs were manufactured by 3D printing with two coding bits, a polylactic acid unit for bit "1" and a water unit for bit "0." BAMs for single- and multi-point focusing through the human skull were designed, 3D printed, and validated numerically and experimentally. The proposed BAMs with subwavelength scale in thickness are simple to design, easy to fabric, and capable of correcting skull aberration and achieving dynamic beam steering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.