Evidence map›Paper›PMID 36117597›Full record

ArticleFrontiers in public health2022

Clinical significance and role of coinfections with respiratory pathogens among individuals with confirmed severe acute respiratory syndrome coronavirus-2 infection.

Ivelina Trifonova, Iva Christova, Iveta Madzharova, Svetla Angelova, Silvya Voleva, Ralitsa Yordanova, Tatiana Tcherveniakova, Stefka Krumova, Neli Korsun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ivelina TrifonovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Iva ChristovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Iveta MadzharovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Svetla AngelovaClinical Virology Laboratory, University Hospital "Prof. Dr. Stoyan Kirkovich", Stara Zagora, Bulgaria.
Silvya VolevaClinic for Neuro Infections, Airborne, Roof, and Transmissible Infections, Infectious Hospital "Prof. Ivan Kirov", Department of Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, Sofia, Bulgaria.
Ralitsa YordanovaClinic for Neuro Infections, Airborne, Roof, and Transmissible Infections, Infectious Hospital "Prof. Ivan Kirov", Department of Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, Sofia, Bulgaria.
Tatiana TcherveniakovaClinic for Neuro Infections, Airborne, Roof, and Transmissible Infections, Infectious Hospital "Prof. Ivan Kirov", Department of Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, Sofia, Bulgaria.
Stefka KrumovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Neli KorsunNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria.
National Center of Infectious and Parasitic Diseases · BGMedical University of Sofia · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to determine the prevalence, viral profile, and clinical features of coinfections with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and other respiratory viruses. Methods: Nasopharyngeal samples and clinical data of 221 hospitalized patients and 21 outpatients were collected and analyzed. Real-time reverse transcription-polymerase chain reaction was used to detect SARS-CoV-2, influenza virus, respiratory syncytial virus (RSV), human metapneumovirus (HMPV), parainfluenza virus (PIV) 1,2,3, rhinovirus (RV), adenovirus (AdV), bocaviruses (BoV), and seasonal coronaviruses (OC43, 229E, NL63, and HKU1). Viral load was determined by capillary electrophoresis. Results: From November 2020 to mid-March 2022, 242 SARS-CoV-2 positive patients were tested for seasonal respiratory viruses, and 24 (9.9%) cases of coinfections were detected. The distribution of viruses involved in cases of coinfections were as follows: HMPV ( Conclusion: In patients aged >65 years, coinfection with SARS CoV-2 and other respiratory viruses, together with concomitant diseases, causes worsening of the clinical picture and complications, and can be fatal. Screening of patients with SARS CoV-2 for other respiratory viruses is needed to select appropriate treatments and prevent a fatal outcome of the disease.

Indexed as

CoinfectionCOVID-19Influenza, HumanAdolescentAgedChildC-Reactive ProteinHumansInfluenza A Virus, H3N2 SubtypeSARS-CoV-2C-Reactive Proteinclinical significancecoinfectionCOVID-19respiratory virusSARS-CoV-2viral load

Identifiers

PMID36117597
PMCPMC9479447
OpenAlexW4294243118

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.