Evidence map›Paper›PMID 36117551›Full record

ArticleGastro hep advances2022

In Vivo Screen Identifies Liver X Receptor Alpha Agonism Potentiates Sorafenib Killing of Hepatocellular Carcinoma.

A M Vázquez Salgado, M E Preziosi, D Yin, A Holczbauer, A M Zahm, N Erez, J Kieckhaefer, D Ackerman, T P Gade, K H Kaestner and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastro hep advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Lipid Nanoparticle Delivery of Small Proteins for PotentACS applied materials & interfaces · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

A M Vázquez SalgadoDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
M E PreziosiDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
D YinDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
A HolczbauerDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
A M ZahmDepartment of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania.
N ErezDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
J KieckhaeferDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
D AckermanPenn Image-Guided Interventions Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
T P GadePenn Image-Guided Interventions Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
K H KaestnerDepartment of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania.
K J WangensteenDivision of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · US

Funding

TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 1997 to 2026
$32.5M
Innovative Genetic Approaches for Hepatic RepopulationR01DK102667 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI KAESTNER, KLAUS H · 2015 to 2019
$1.8M
Genetic basis of liver repopulationK08DK106478 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WANGENSTEEN, KIRK J · 2015 to 2019
$787k
Role of microRNAs in pediatric inflammatory bowel diseaseK01DK102868 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ZAHM, ADAM MATTHEW · 2015 to 2019
$665k
NIDDK NIH HHS K01 DK102868NIDDK NIH HHS K08 DK106478NIDDK NIH HHS P30 DK050306NIDDK NIH HHS R01 DK102667
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID36117551
PMCPMC9481113
OpenAlexW4281654169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.