Evidence map›Paper›PMID 36117501›Full record

ArticleChinese herbal medicines2021

Evaluation of anti-inflammatory and anti-arthritic property of ethanolic extract of

K P Swathi, Saravanan Jayaram, Deepa Sugumar, Emdormi Rymbai

Open access · goldAbstract read
In one paragraph

Article in Chinese herbal medicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

K P SwathiDepartment of Pharmacology, KMCH College of Pharmacy, Tamil Nadu Dr. M. G. R. Medical University, Coimbatore 641048, India.
Saravanan JayaramDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty 643001, India.
Deepa SugumarDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty 643001, India.
Emdormi RymbaiDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty 643001, India.
JSS Academy of Higher Education and Research · INTamil Nadu Dr. M.G.R. Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Methods: The anti-inflammatory activity of the EECT was evaluated by carrageenan and histamine-induced paw edema. Results: EECT showed a significant reduction in mean paw edema volume in both carrageenan and histamine-induced inflammation. The efficacy of EECT in rheumatoid arthritis was tested against Freund's complete adjuvant (CFA) induced arthritic model in Wistar rats. The anti-arthritic effect of EECT was determined by systematic scoring of arthritis symptoms and measuring paw edema. A considerable decrease in paw diameter was observed in the EECT (200 and 400 mg/kg) and diclofenac (10 mg/kg) treated groups after day 7. Diclofenac (10 mg/kg) and EECT (400 mg/kg) showed a significant reduction in paw diameter from day 14 compared with CFA control ( Conclusion: This study provides a pharmacological rationale for the traditional use of

Indexed as

antioxidantsClitoria ternatea Linn.inflammationrheumatoid arthritis

Identifiers

PMID36117501
PMCPMC9476680
OpenAlexW3108599917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.