GuidelineJournal of evidence-based medicine2022
Clinical guideline for the diagnosis and treatment of cutaneous warts (2022).
Guideline in Journal of evidence-based medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06691542 (Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts), which is not on this map. Cited by 48 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts
Who cites it
48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Efficacy and safety of superficial radiotherapy in the treatment of cutaneous warts: A meta-analysis.The Journal of international medical research · 2026Pooled it
- Pooled it
- Efficacy and Safety of Ionic Contra-viral Therapy (Digoxin-furosemide) in the Treatment of Multiple Cutaneous Warts: A Systematic Review, Meta-analysis, and Trial Sequential Analysis.Current drug research reviews · 2026Pooled it
- The Effects of Podophyllotoxin Derivatives on Noncancerous Diseases: A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Clinical guideline for the diagnosis and treatment of cutaneous warts (2022).Journal of evidence-based medicine · 2022Guideline
- Clinical Efficacy of 5-Aminolevulinic Acid Photodynamic Therapy Combined With Interferon Spray in Treating Common and Plantar Warts.Photodermatology, photoimmunology & photomedicine · 2026Trial
- Intralesional Interferon Alfa-2b Versus Cryotherapy for Common Warts on the Hands and Feet: A Randomized, Open-Label, Controlled Trial.Journal of cosmetic dermatology · 2026Trial
- [7/f-Hyperkeratotic papules and plaques existing for 2 years : Preparation for the medical specialist examination: part 73].Dermatologie (Heidelberg, Germany) · 2026Article
- Differential Signature of Gut Microbiota in Female Patients with Condyloma Acuminatum and Its Association with Persistent Human Papillomavirus Infection.Journal of clinical medicine · 2026Article
- Molecular insights and therapeutic innovations in low-risk human papillomavirus-associated cutaneous wart.Molecular biology reports · 2026Review
- Comparative Efficacy and Safety of Non-Cryotherapy Treatments Versus Cryotherapy for Plantar Warts: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2026Review
- Gene Expression of Suppressor of Cytokine Signaling 3 (SOCS3), Interferons Alpha and Beta (IFN-α and β) in Common Warts.Indian dermatology online journal · 2026Article
- Efficacy and safety of digoxin/furosemide for cutaneous warts: a systematic review and meta-analysis of eight randomized controlled trials.Annals of medicine and surgery (2012) · 2026Article
- Treatment of flat warts with trifarotene.Dermatology reports · 2026Article
- New Insights into Infectious Skin and Mucosal Diseases: Translating Epidemiological Shifts into Tailored Clinical Practice.Journal of clinical medicine · 2026Article
- International expert consensus on transdermal drug delivery technologies in dermatology.JAAD international · 2026Article
- Article
- Giant condyloma acuminatum in a patient with HIV infection: a case report.AIDS research and therapy · 2026Article
- Article
- Cutaneous papillomaviruses infection rewires fatty-acid metabolism.Frontiers in cellular and infection microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
37 authors at 20 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimCutaneous warts caused by human papillomavirus are benign proliferative lesions that occur at any ages in human lives. Updated, comprehensive and systematic evidence-based guidelines to guide clinical practice are urgently needed.
methodsWe collaborated with multidisciplinary experts to formulate this guideline based on evidences of already published literature, focusing on 13 clinical questions elected by a panel of experts. We adopted Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to form classification of recommendations as well as the improved Delphi method to retain respective recommendations with a consensus degree of over 80%.
resultsOur guideline covered aspects of the diagnosis and treatment of cutaneous warts such as diagnostic gold standard, transmission routes, laboratory tests, treatment principle, clinical cure criterion, definitions, and treatments of common warts, flat warts, plantar warts, condyloma acuminatum, and epidermodysplasia verruciformis. Recommendations about special population such as children and pregnant women are also listed. In total, 49 recommendations have been obtained.
conclusionsIt is a comprehensive and systematic evidence-based guideline and we hope this guideline could systematically and effectively guide the clinical practice of cutaneous warts and improve the overall levels of medical services.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.