Evidence map›Paper›PMID 36116132›Full record

ArticleThe British journal of radiology2022

A CT-based pelvic calcification score in kidney transplant patients is a possible predictor of graft and overall survival.

Iva Žuža, Doris Dodig, Ivan Brumini, Dorian Tokmadžić, Lidija Orlić, David Zgrablić, Ivan Vukelić, Antun Gršković, Nataša Katalinić, Ante Jakšić and 3 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05697458 (Evaluation and Prognostic Value of Iliac Arterial Calcifications Determined With Computerized Tomography and Bone Remodeling Biomarkers in Patients With Kidney Transplantation), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05697458 completednot on this map

Evaluation and Prognostic Value of Iliac Arterial Calcifications Determined With Computerized Tomography and Bone Remodeling Biomarkers in Patients With Kidney Transplantation

TypeobservationalSponsorClinical Hospital Center RijekaRan2022 to 2024Enrolled70ConditionsArterial Calcification, Kidney Failure, Kidney Transplant, ComplicationsArmscomputerized tomography scanning
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Iva ŽužaDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Doris DodigDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Ivan BruminiDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Dorian TokmadžićFaculty of Medicine, University of Rijeka, Rijeka, Croatia.
Lidija OrlićDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
David ZgrablićFaculty of Medicine, University of Rijeka, Rijeka, Croatia.
Ivan VukelićDepartment of Urology, University Hospital Rijeka, Rijeka, Croatia.
Antun GrškovićDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Nataša KatalinićDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Ante JakšićDepartment of Urology, University Hospital Rijeka, Rijeka, Croatia.
Damir MiletićDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Sanjin RačkiDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.
Dean MarkićDepartment of Radiology, University Hospital Rijeka, Rijeka, Croatia.ORCID 0000-0001-5696-0850
University of Rijeka · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesComputerized tomography (CT) is the most accurate method for evaluating pelvic calcifications, which are of utmost importance for planning kidney transplantation (KT). The aim of our study was to evaluate the incidence and distribution of iliac artery calcifications and correlate the novel pelvic calcification score (PCS) with cardiovascular risk factors and graft and overall survival in KT patients.

methodsWe retrospectively included 118 KT patients operated at our institution with pretransplant pelvic CT. Calcification morphology, circumference and length of both common and external iliac arteries were independently scored by two uroradiologists. PCS was calculated as the total score sum of all three calcification features in all vessels. PCS correlation with graft and patient survival was performed.

resultsCalcification in at least one vascular segment was found in 79% of patients. PCS was significantly higher in male patients (

conclusionsThe extent of iliac artery calcification in KT recipients quantified by PCS on pretransplant CT correlates with graft and overall patient survival. A PCS over three was associated with worse clinical outcomes and could become a possible prognostic factor. ADVANCES IN KNOWLEDGE: Our novel PCS is a robust method for quantifying iliac artery calcification burden. Since higher a PCS correlates with worse patient and graft survival, PCS has the potential to become a prognostic factor in kidney transplant patients.

Indexed as

Kidney TransplantationVascular CalcificationGraft SurvivalHumansMaleRetrospective StudiesRisk FactorsTomography, X-Ray Computed

Identifiers

PMID36116132
PMCPMC9793470
OpenAlexW4296249002

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.