ArticleJournal of cardiac surgery2022
Females have an increased risk of short-term mortality after cardiac surgery compared to males: Insights from a national database.
Article in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of differences between men and women in short-term outcomes following coronary artery bypass graft surgery.Scientific reports · 2024Pooled it
- Sex Disparities in Outcomes After Minimally Invasive Direct CABG for Single-Vessel Disease: A Propensity Score-Matched Analysis.Journal of clinical medicine · 2026Article
- The role of sex in multiarterial coronary artery bypass grafting: A landmark and risk factor analysis.JTCVS open · 2026Article
- Sex impacts outcome in minimally invasive surgery of the ascending aorta: a propensity score matched analysis.Journal of cardiothoracic surgery · 2026Article
- Sex disparities in coronary re-vascularisation and mortality.BMC cardiovascular disorders · 2026Article
- Article
- Postoperative adverse events after spinal surgery: Sex-specific risk profiles and ICU utilization.Brain & spine · 2026Article
- Incidence and Predictors of Surgical Site Infection in Patients Undergoing Coronary Artery Bypass Grafting at a Reference Hospital in Brazil: Influence of Sex, Nutritional Risk, and Body Mass Index.Brazilian journal of cardiovascular surgery · 2026Article
- Impact of Atrial Fibrillation on Hospital Outcomes in NSTEMI Patients: A Retrospective Cohort Study.Journal of community hospital internal medicine perspectives · 2026Article
- Interest in cardiothoracic surgery: are women more interested today?Indian journal of thoracic and cardiovascular surgery · 2026Review
- Circulatory Support for High-Risk Coronary Artery Bypass Grafting and Coronary Interventions: Where is the Evidence?The International journal of angiology : official publication of the International College of Angiology, Inc · 2025Review
- Addressing Sex Disparities in Coronary Revascularization among Dialysis Patients: A Call for Equity and Precision.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database.Journal of the American Heart Association · 2025Article
- Female Surgeons in Cardiac Surgery: Does the Surgeon's Gender Affect the Outcome of Routine Coronary Artery Bypass Graft and Isolated Aortic Valve Surgery?The Thoracic and cardiovascular surgeon · 2025Article
- Healthcare disparities in adult and pediatric spinal deformity: a state of the art review.Spine deformity · 2025Review
- Sex based disparities in hospitalization and readmission outcomes for complete atrioventricular block: Insights from United States readmission data.Journal of arrhythmia · 2025Article
- Female sex is associated with short-term mortality in coronary artery bypass grafting patients: A propensity-matched analysis.Heliyon · 2025Article
- Observational
- Prognostic value of neutrophil-lymphocyte ratio, absolute lymphocyte count, and thrombocyte-lymphocyte ratio in predicting the outcomes of tetralogy of fallot primary repair.Frontiers in cardiovascular medicine · 2025Article
- Sex difference in outcomes after coronary artery bypass grafting: follow-up data of the Netherlands Heart Registration.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
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8 authors.
Funding
Abstract
objectivesFemale sex is considered a risk factor for mortality and morbidity following cardiac surgery. This study is the first to review the UK adult cardiac surgery national database to compare outcomes following surgical coronary revascularisation and valvular procedures between females and males.
methodsUsing data from National Adult Cardiac Surgery Audit, we identified all elective and urgent, isolated coronary artery by-pass grafting (CABG), aortic valve replacement (AVR) and mitral valve replacement/repair (MVR) procedures from 2010 to 2018. We compared baseline data, operative data and outcomes of mortality, stroke, renal failure, deep sternal wound infection, return to theater for bleeding, and length of hospital stay. Multivariable mixed-effect logistical/linear regression models were used to assess relationships between sex and outcomes, adjusting for baseline characteristics.
resultsFemales, compared to males, had greater odds of experiencing 30-day mortality (CABG odd ratio [OR] 1.76, confidence interval [CI] 1.47-2.09, p < .001; AVR OR 1.59, CI 1.27-1.99, p < .001; MVR OR 1.37, CI 1.09-1.71, p = .006). After CABG, females also had higher rates of postoperative dialysis (OR 1.31, CI 1.12-1.52, p < .001), deep sternal wound infections (OR 1.43, CI 1.11-1.83, p = .005) and longer length of hospital stay (β 1.2, CI 1.0-1.4, p < .001) compared to males. Female sex was protective against returning to theater for postoperative bleeding following CABG (OR 0.76, CI 0.65-0.87, p < .001) and AVR (OR 0.72, CI 0.61-0.84, p < .001).
conclusionFemales in the United Kingdom have an increased risk of short-term mortality after cardiac surgery compared to males. This highlights the need to focus on the understanding of the causes behind these disparities and implementation of strategies to improve outcomes in females.
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