ArticleArchives of public health = Archives belges de sante publique2022
Burden and trends of brain and central nervous system cancer from 1990 to 2019 at the global, regional, and country levels.
Article in Archives of public health = Archives belges de sante publique, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 137 citations in OpenAlex.
- Occupational Diesel Exposure and Brain Tumors: A Systematic Review and Meta-Analysis.La Medicina del lavoro · 2025Pooled it
- Pooled it
- Oleanolic acid in the fight against cancer: a multifaceted natural strategy for modern oncology.Molecular diversity · 2026Review
- Development of a neural network predicting signals for time-domain diffuse optical tomography.Biomedical engineering letters · 2026Article
- Global Burden and Temporal Trends of Brain and Central Nervous System Tumors in Children and Adolescents: A Systematic Analysis for the Global Burden of Disease Study 2021.Cancer innovation · 2026Article
- The top 100 most cited peer-reviewed publications on global neurosurgery: Mapping research trends and gaps over four decades.Acta neurochirurgica · 2026Review
- Variation in rates of post-operative oncological treatment for patients with glioblastoma in England: a comprehensive multi-year National cohort study from the GlioCova project.Journal of neuro-oncology · 2026Article
- Translation and Validation of the Neurologic Assessment in Neuro-Oncology Scale into Indonesian (NANO-Ina).Asian Pacific journal of cancer prevention : APJCP · 2026Article
- BrainView: A cloud-based deep learning system for brain image segmentation, tumor detection and visualization.Biomedical journal · 2026Article
- The public health burden of nervous system tumors in Anambra State, Nigeria necessitates strategic resource allocation.Scientific reports · 2026Article
- Venous thromboembolism and secondary outcomes of bleeding and mortality in patients with gliomas: a multicenter cohort study.Frontiers in oncology · 2026Article
- Epidemiological trends of burden of brain and CNS cancer at global, regional, and national level: a trend analysis study from 1990 to 2021.European journal of medical research · 2025Article
- Gaps in Diagnosis, Treatment, and Outcomes Among Patients with Brain Tumors in the United States: A State-of-the-Art Review.Cancers · 2025Review
- Unsupervised generative AI for enhancing brain tumor segmentation in multi-center, incomplete real-world data scenarios.NPJ precision oncology · 2025Article
- Role of Colony Stimulating Factor 1 (CSF-1) and Its Receptor CSF1R: Macrophage Repolarization for Glioblastoma Treatment.ACS pharmacology & translational science · 2025Review
- Primary Pediatric Brain Tumors in a Tertiary Referral Center in Iran: A 13-Year Retrospective Analysis.Archives of Iranian medicine · 2025Article
- Thioflavin T Lasing Probe for Mucin Detection in Simulated Tears as a Targeting Strategy for Brain Tumors.ACS chemical neuroscience · 2025Article
- The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021.Scientific reports · 2025Article
- Global trends and burden of brain and central nervous system cancers in adolescents and young adults GBD 2021 study.Scientific reports · 2025Article
- Actuated Hydrogel Platforms To Study Brain Cell Behavior.Advanced healthcare materials · 2025Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRegularly updated epidemiological data on the burden of brain and central nervous system (CNS) cancers are important in the prioritization of research and the allocation of resources. This study aimed to investigate incidence, mortality, disability, and trends in brain and CNS cancers between 1990 and 2019.
methodsEpidemiological data, including the cancer incidence, mortality, disability-adjusted life years(DALYs), age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized DALY rate (per 100,000 population) stratified by region, country, sex, and age group were retrieved and extracted using the Global Health Data Exchange (GHDx) query tool.
resultsIn 2019, there were 347,992(262,084-388,896) global cases of brain and CNS cancers, which showed a significant increase (94.35%) from the period between 1990 to 2019. The global ASIR in 2019 was 4.34 (3.27-4.86) per 100, 000 population, which showed an increasing trend for the years 1990-2019 (13.82% [-27.27-32.83]). In 2019, there were 246,253 (185,642-270,930) global deaths caused by brain and CNS cancers, which showed a significant increase (76.36%) during the study period. The global ASMR in 2019 was 3.05(2.29-3.36) per 100, 000 population, which did not change significantly over the study period (-1.19% [-36.79-13.86]). In 2019, there were 8,659,871 DALYs, which was a 109.04% increase compared with 1990. Similarly, during 1990-2019, the age-standardized DALY rate decreased by 10.39%. Additionally, 76.60% of the incident cases, 72.98% of the deaths, and 65.16% of the DALYs due to brain and CNS cancers occurred in the high-income and upper-middle-income regions.
conclusionsIn conclusion, brain and CNS cancers remain a major public health burden, particularly in high-income regions. The global incidence, deaths, and DALYs of brain and CNS cancers were shown to have increased significantly from 1990 to 2019. The global ASIR kept rising steadily, while the ASMR and age-standardized DALY rate declined over the past three decades.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.