Evidence map›Paper›PMID 36115665›Full record

Observational studyBMJ open2022

Study protocol to explore the social effects of environmental exposure and lifestyle behaviours on pregnancy outcome: an overview of cohort of pregnant women study.

Valentin Simoncic, Virginie Hamann, Loriane Huber, Phillipe Deruelle, Nicolas Sananes, Christophe Enaux, Maxime Alter, Charles Schillinger, Severine Deguen, Wahida Kihal-Talantikite

2 registry-linked trialsOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04705272 unknown statusnot on this map

The Role of the Living Environment in the Social Inequalities in the Physical Activities of Pregnant Women Residing in the Eurometropole of Strasbourg

TypeobservationalSponsorUniversity Hospital, Strasbourg, FranceRan2021 to 2022Enrolled800ConditionsPhysical Activity of Pregant WomenArmsQuestionnaire
NCT04725734 unknown statusnot on this map

Air Pollution and Daily Mobility of Pregnant Women in the Eurometropole: Identification of Critical Windows of Exposure During Pregnancy

TypeobservationalSponsorUniversity Hospital, Strasbourg, FranceRan2021 to 2022Enrolled800ConditionsPregnancy, Low Birth Weight, Preterm Birth, Air PollutionArmsPregnant women
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The impact of the Social Exposome in Cardiovascular Health and Disease.Journal of precision medicine (Amsterdam, Netherlands) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Valentin SimoncicUniversity of Strasbourg, LIVE UMR 7362 CNRS (Laboratoire Image Ville Environnement), Strasbourg, France.ORCID 0000-0002-0879-8534
Virginie HamannUniversity of Strasbourg, LIVE UMR 7362 CNRS (Laboratoire Image Ville Environnement), Strasbourg, France.
Loriane HuberDepartment of Obstetrics and Gynaecology, University Hospitals Strasbourg, Strasbourg, France.
Phillipe DeruelleDepartment of Obstetrics and Gynaecology, University Hospitals Strasbourg, Strasbourg, France.
Nicolas SananesDepartment of Obstetrics and Gynaecology, University Hospitals Strasbourg, Strasbourg, France.
Christophe EnauxUniversity of Strasbourg, LIVE UMR 7362 CNRS (Laboratoire Image Ville Environnement), Strasbourg, France.
Maxime AlterATMO Grand Est, Strasbourg, France.
Charles SchillingerATMO Grand Est, Strasbourg, France.
Severine DeguenPHARes Inserm CIC 140, Bordeaux Population Health Research Center, University of Bordeaux, Talence, Aquitaine, France.
Wahida Kihal-TalantikiteUniversity of Strasbourg, LIVE UMR 7362 CNRS (Laboratoire Image Ville Environnement), Strasbourg, France wahida.kihal@live-cnrs.unistra.fr.
Centre National de la Recherche Scientifique · FRAtmel (France) · FRHôpitaux Universitaires de Strasbourg · FRInserm · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA growing number of international studies have highlighted the adverse consequences of lived experience in the first thousand days of pregnancy and early life on the probability of stillbirth, child mortality, inadequate growth and healthy development during both childhood and adulthood. The lived experience of the fetus inside the womb and at the birth is strongly related to both maternal health during pregnancy and maternal exposure to a set of environmental factors known as 'exposome' characteristics, which include environmental exposure, health behaviours, living conditions, neighbourhood characteristics and socioeconomic profile. The aim of our project is to explore the relationships between exposome characteristics and the health status of pregnant women and their newborns. We are particularly interested in studying the relationships between the social inequality of adverse pregnancy outcomes and (1) short-term exposure to atmospheric pollution (MobiFem project) and (2) pregnancy lifestyle (EnviFem project). METHODS AND ANALYSIS: Ours is a prospective, observational and multisite cohort study of pregnant women, involving one teaching hospital across two sites in the Strasbourg metropolitan area.The research team at University Hospital of Strasbourg (HUS) Health collects data on outcomes and individual characteristics from pregnancy registries, clinical records data and questionnaires administered via email to study participants. Recruitment began in February 2021 and will be complete by December 2021. Participants are recruited from first trimester antenatal ultrasound examinations (conducted on weekdays across both sites); each woman meeting our inclusion criteria enters the cohort at the end of her first trimester. Study participants receive a total of three online questionnaires covering sociodemographic characteristics, travel behaviour patterns and lifestyle. Participants complete these questionnaires at recruitment, during the second and third trimester. The level of personal exposure to air pollution is characterised using a dynamic spatiotemporal trajectory model that describes the main daily movements of pregnant women and the time spent in each place frequented. Univariate, multilevel and Bayesian model will be used to investigate the relationships between exposome characteristics and the health status of pregnant women and their newborns. ETHICS AND DISSEMINATION: Our research was approved by the Commission de Protection des Personnes (CPP) Ile de France VI (Paris) on 9 December 2020 (File reference No. 20.09.15.41703 ID RCB: 2020-A02580-39 and No. 20 080-42137 IDRCB 2020-A02581-38). The Agence Nationale de Sécurité du Médicament was informed of it on 15 December 2020. Findings from the study will be disseminated through publications and international conferences and through presentation at meetings with local stakeholders, researchers and policy-makers. TRIAL REGISTRATION NUMBERS: NCT04705272, NCT04725734.

Indexed as

Environmental ExposurePregnant PeopleAdultBayes TheoremChildCohort StudiesFemaleHumansInfant, NewbornLife StylePregnancyPregnancy OutcomeProspective Studiesepidemiologyfetal medicinepublic health

Identifiers

PMID36115665
PMCPMC9486210
OpenAlexW4296248374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.