Evidence map›Paper›PMID 36115589›Full record

ArticleNeuroImage2022

Do sparse brain activity patterns underlie human cognition?

Iiro P Jääskeläinen, Enrico Glerean, Vasily Klucharev, Anna Shestakova, Jyrki Ahveninen

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Iiro P JääskeläinenBrain and Mind Laboratory, Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland; International Laboratory of Social Neurobiology, Institute of Cognitive Neuroscience, HSE University, Moscow, Russian Federation.
Enrico GlereanBrain and Mind Laboratory, Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland; International Laboratory of Social Neurobiology, Institute of Cognitive Neuroscience, HSE University, Moscow, Russian Federation.
Vasily KlucharevInternational Laboratory of Social Neurobiology, Institute of Cognitive Neuroscience, HSE University, Moscow, Russian Federation.
Anna ShestakovaInternational Laboratory of Social Neurobiology, Institute of Cognitive Neuroscience, HSE University, Moscow, Russian Federation.
Jyrki AhveninenMassachusetts General Hospital, Harvard Medical School, Massachusetts Institute of Technology Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA, United States.
National Research University Higher School of Economics · RUAalto University · FIAthinoula A. Martinos Center for Biomedical Imaging · US

Funding

Mapping the intrinsic functional organization of auditory cortex in individual subjects using 7T MRIR01DC017991 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI AHVENINEN, JYRKI · 2019 to 2023
$4.0M
Decoding parametric attributes of auditory working memories from human brain activityR01DC016915 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI AHVENINEN, JYRKI · 2018 to 2022
$3.0M
Non-invasive measures of multisensory cortical feedforward and feedback influencesR01DC016765 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI AHLFORS, SEPPO PENTTI, AHVENINEN, JYRKI · 2018 to 2022
$2.7M
NIDCD NIH HHS R01 DC016765NIDCD NIH HHS R01 DC016915NIDCD NIH HHS R01 DC017991
6 · The paper itself

Abstract

Accumulating multivariate pattern analysis (MVPA) results from fMRI studies suggest that information is represented in fingerprint patterns of activations and deactivations during perception, emotions, and cognition. We postulate that these fingerprint patterns might reflect neuronal-population level sparse code documented in two-photon calcium imaging studies in animal models, i.e., information represented in specific and reproducible ensembles of a few percent of active neurons amidst widespread inhibition in neural populations. We suggest that such representations constitute a fundamental organizational principle via interacting across multiple levels of brain hierarchy, thus giving rise to perception, emotions, and cognition.

Indexed as

Brain MappingCognitionAnimalsBrainEmotionsHumansMagnetic Resonance ImagingMultivariate AnalysisCognitionEmotionsfMRIMVPAPerceptionSparse distributed representations

Identifiers

PMID36115589
PMCPMC10921366
OpenAlexW4295779211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.