Evidence map›Paper›PMID 36115252›Full record

ReviewCurrent opinion in neurobiology2022

Spatiotemporal dynamics in large-scale cortical networks.

Michael J Higley, Jessica A Cardin

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. WidefieldNeurophotonics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael J HigleyDepartments of Neuroscience and Psychiatry, Kavli Institute for Neuroscience, Wu Tsai Institute, Yale University, New Haven, CT, USA.
Jessica A CardinDepartments of Neuroscience and Psychiatry, Kavli Institute for Neuroscience, Wu Tsai Institute, Yale University, New Haven, CT, USA. Electronic address: jess.cardin@yale.edu.

Funding

Yale Core Grant for Vision ResearchP30EY026878 · NEI · YALE UNIVERSITY · PI Z JIMMY ZHOU · 2016 to 2026
$7.1M
Bridging cellular and systems neuroscience: synaptic dynamics underlying behaviorDP1EY033975 · NEI · YALE UNIVERSITY · PI HIGLEY, MICHAEL JAMES · 2021 to 2025
$5.9M
Cellular mechanisms of GABAergic inhibition in neocortical dendritesR01MH099045 · NIMH · YALE UNIVERSITY · PI Michael James Higley · 2012 to 2026
$5.7M
Inhibitory regulation of cortical visual processingR01EY022951 · NEI · YALE UNIVERSITY · PI CARDIN, JESSICA A · 2013 to 2025
$4.0M
Role of GABAergic interneurons in developmental dysregulation of cortical functionR01MH113852 · NIMH · YALE UNIVERSITY · PI CARDIN, JESSICA A, HIGLEY, MICHAEL JAMES · 2017 to 2021
$2.1M
Cellular mechanisms of GABAergic inhibition in neocortical dendritesR56MH099045 · NIMH · YALE UNIVERSITY · PI HIGLEY, MICHAEL JAMES · 2024 to 2024
$606k
Behavior-dependent classification of neocortical cell typesR21MH121841 · NIMH · YALE UNIVERSITY · PI HIGLEY, MICHAEL JAMES · 2020 to 2021
$461k
NEI NIH HHS DP1 EY033975NEI NIH HHS P30 EY026878NEI NIH HHS R01 EY022951NIMH NIH HHS R01 MH099045NIMH NIH HHS R01 MH113852NIMH NIH HHS R21 MH121841NIMH NIH HHS R56 MH099045
6 · The paper itself

Abstract

Investigating links between nervous system function and behavior requires monitoring neuronal activity at a range of spatial and temporal scales. Here, we summarize recent progress in applying two distinct but complementary approaches to the study of network dynamics in the neocortex. Mesoscopic calcium imaging allows simultaneous monitoring of activity across most of the cortex at moderate spatiotemporal resolution. Electrophysiological recordings provide extremely high temporal resolution of neural signals at multiple targeted locations. A number of recent studies have used these tools to reveal novel patterns of activity across distributed cortical subnetworks. This growing body of work strongly supports the hypothesis that the dynamic coordination of spatially distinct regions is a fundamental aspect of cortical function that supports cognition and behavior.

Indexed as

NeocortexCalciumCognitionElectrophysiological PhenomenaNeuronsCalcium

Identifiers

PMID36115252
PMCPMC10618958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.