Evidence map›Paper›PMID 36115234›Full record

ArticleFood chemistry2023

Chromatographic fractionation of food-grade oligosaccharides: Recognizing and avoiding sensory-relevant impurities.

Toren S Andrewson, Laura E Martin, Juyun Lim, Michael H Penner

Abstract read
In one paragraph

Article in Food chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Toren S AndrewsonDepartment of Food Science and Technology, Oregon State University, Corvallis, OR, USA.
Laura E MartinDepartment of Food Science and Technology, Oregon State University, Corvallis, OR, USA.
Juyun LimDepartment of Food Science and Technology, Oregon State University, Corvallis, OR, USA. Electronic address: Juyun.Lim@oregonstate.edu.
Michael H PennerDepartment of Food Science and Technology, Oregon State University, Corvallis, OR, USA. Electronic address: Mike.Penner@oregonstate.edu.

Funding

Oral Complex Carbohydrate SensingR01DC017555 · NIDCD · OREGON STATE UNIVERSITY · PI LIM, JUYUN · 2020 to 2023
$1.3M
NIDCD NIH HHS R01 DC017555
6 · The paper itself

Abstract

Flash chromatography utilizing microcrystalline cellulose (MCC) stationary phases and aqueous ethanol mobile phases have shown promise for the production of food-grade oligosaccharides. The current work extends the scope of these systems by demonstrating their use for the production of food-grade maltooligosaccharide preparations enriched in high degree of polymerization (DP) components. Furthermore, it is shown herein that caution must be exercised when using these MCC-based chromatographic systems in order to avoid sensory-relevant contamination of the final oligosaccharide preparations. Such contamination, most notably off-taste, is shown to arise from impurities common to commercially available MCC that manifest under certain chromatographic scenarios. A mitigation strategy based on washing the stationary phase with appropriate aqueous-ethanol solutions (i.e., accounting for the entire mobile phase concentration range) prior to oligosaccharide fractionation is presented as a means by which to avoid contamination.

Indexed as

Chemical FractionationChromatographyEthanolOligosaccharidesWaterEthanolOligosaccharidesWaterCelluloseChromatographyImpuritiesOff-tasteOligosaccharidesSeparation

Identifiers

PMID36115234
PMCPMC9945451

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.