Evidence map›Paper›PMID 36115001›Full record

ArticleInternational journal of clinical pharmacy2022

Additional value of a triggerlist as selection criterion in identifying patients at high risk of medication-related hospital admission: a retrospective cohort study.

A E M J H Linkens, M J M Janssen, N van Nie, L Peeters, B Winkens, V Milosevic, B Spaetgens, K P G M Hurkens, P H M van der Kuy

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Article in International journal of clinical pharmacy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

A E M J H LinkensDepartment of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Centre, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. aimee.linkens@mumc.nl.ORCID http://orcid.org/0000-0002-9252-7656
M J M JanssenDepartment of Internal Medicine, Zuyderland Medical Centre, Sittard, Geleen, The Netherlands.
N van NieDepartment of Research, Innnovation and Funding, Zuyderland Medical Centre, Heerlen, Limburg, The Netherlands.
L PeetersGeneral Pharmacist, Heerlen, The Netherlands.
B WinkensDepartment of Methodology and Statistics, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.
V MilosevicClinical Pharmacy, Elkerliek Hospital, Helmond, The Netherlands.
B SpaetgensDepartment of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Centre, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
K P G M HurkensDepartment of Internal Medicine, Geriatric Medicine, Zuyderland Medical Centre, Sittard, Geleen, The Netherlands.
P H M van der KuyDepartment of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, 3015 GD, Rotterdam, The Netherlands.
Zuyderland Medisch Centrum · NLMaastricht University Medical Centre · NLElkerliek Ziekenhuis · NLErasmus MC · NLMaastricht University · NL

Funding

ZonMw 848016012
6 · The paper itself

Abstract

backgroundOf all hospital admissions in older patients, 10-30% seem to be medication-related. However, medication-related admissions are often unidentified in clinical practice. To increase the identification of medication-related hospital admissions in older patients a triggerlist is published in the Dutch guideline for polypharmacy.

aimTo assess whether the triggerlist has value as selection criterion to identify patients at high risk of medication-related hospital admissions.

methodThis retrospective cohort study was carried out in 100 older (≥ 60 years) patients with polypharmacy and having two triggers from the triggerlist. The admissions were assessed as either possibly or unlikely medication-related according to the Assessment Tool for identifying Hospital Admissions Related to Medications.

resultsOf all the admissions 48% were classified as possibly medication-related. Patients with a possible medication-related hospital admission were more likely to have an impaired renal function (p = 0.015), but no differences with regard to age, sex, comorbidity or number of medicines were found.

conclusionThe high prevalence of medication-related hospital admissions, suggests the triggerlist may have added value as selection criterion in a cohort of older patients with polypharmacy and can be used to improve the identification of a population at high risk of medication-related hospital admissions.

Indexed as

HospitalizationPolypharmacyAgedCohort StudiesHospitalsHumansRetrospective StudiesAgedHospitalizationMedication errorsPolypharmacyTriggerlist

Identifiers

PMID36115001
OpenAlexW4296164613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.