Evidence map›Paper›PMID 36114939›Full record

ArticleBreast cancer research and treatment2022

Ductal carcinoma in situ of the male breast: clinical radiological features and management in a cancer referral center.

Luca Nicosia, Germana Lissidini, Manuela Sargenti, Anna Carla Bozzini, Gabriel Farante, José Vila, Chiara Oriecuia, Eleonora Pagan, Vincenzo Bagnardi, Matteo Lazzeroni and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Breast cancer research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Male Breast Cancer: Current Scenario and Future Perspectives.Technology in cancer research & treatment
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Luca Nicosia *Department of Breast Radiology, European Institute of Oncology (IEO), IRCCS, 20141, Milan, Italy. luca.nicosia@ieo.it.ORCID http://orcid.org/0000-0003-3979-8075
Germana Lissidini *Division of Breast Surgery, European Institute of Oncology (IEO), IRCCS, Milan, Italy.
Manuela SargentiDivision of Breast Surgery, European Institute of Oncology (IEO), IRCCS, Milan, Italy.
Anna Carla BozziniDepartment of Breast Radiology, European Institute of Oncology (IEO), IRCCS, 20141, Milan, Italy.
Gabriel FaranteDivision of Breast Surgery, European Institute of Oncology (IEO), IRCCS, Milan, Italy.
José VilaHospital Universitario y Politécnico La Fe, Valencia, Spain.
Chiara OriecuiaDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Eleonora PaganDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.
Vincenzo BagnardiDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.
Matteo LazzeroniDivision of Cancer Prevention and Genetics, European Institute of Oncology (IEO), IRCCS, Milan, Italy.
Filippo PesapaneDepartment of Breast Radiology, European Institute of Oncology (IEO), IRCCS, 20141, Milan, Italy.
Claudia SangalliData Management, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Viviana GalimbertiDivision of Breast Surgery, European Institute of Oncology (IEO), IRCCS, Milan, Italy.
Enrico CassanoDepartment of Breast Radiology, European Institute of Oncology (IEO), IRCCS, 20141, Milan, Italy.
Paolo VeronesiDivision of Breast Surgery, European Institute of Oncology (IEO), IRCCS, Milan, Italy. paolo.veronesi@ieo.it.
European Institute of Oncology · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Milano-Bicocca · ITData Management (Italy) · ITHospital Universitari i Politècnic La Fe · ESUniversity of Brescia · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present an overview of the management of male patients with Ductal Carcinoma In Situ of the breast (male DCIS).

methodsWe retrospectively studied all male patients with a diagnosis of pure DCIS from January 1999 to December 2018: 20 patients were identified in our cancer referral center. We collected data regarding clinical presentation, age of onset, radiological features, receptor status of the neoplasm, histological type, and the follow-up of those patients.

resultsThe median age was 62 years (range 21-80). All patients underwent surgery, in 15/20 (75%) cases a mastectomy was carried out. Two patients (10%) underwent endocrine treatment and 1/20 (5%) underwent radiotherapy. The receptor status for 15/20 patients was documented: 13/15 patients were ER+/Pr+. In 3 cases the Ki 67% was positive (i.e., > 20%). All cases were negative for Her2. The median follow-up time was 9.0 years (IQR 4.0-13.7). Only one patient had an ipsilateral recurrence with the finding of an infiltrating carcinoma in the same breast after 14 years. The 5-year disease-free survival was 92.9%.

conclusionPure DCIS in men is an extremely rare disease: proper diagnosis and management allow an excellent prognosis.

Indexed as

Breast NeoplasmsBreast Neoplasms, MaleCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingAdultAgedAged, 80 and overHumansKi-67 AntigenMaleMastectomyMastectomy, SegmentalMiddle AgedNeoplasm Recurrence, LocalReferral and ConsultationRetrospective StudiesKi-67 AntigenBreastDisease-free survivalMale DCISSurgery

Identifiers

PMID36114939
PMCPMC9581867
OpenAlexW4296157756

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.