Evidence map›Paper›PMID 36114936›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2023

Hospital outcomes of patients receiving catheter ablation of atrial fibrillation, left atrial appendage closure, or both.

Ramez Morcos, Haider Al Taii, Muni Rubens, Anshul Saxena, Venkataraghavan Ramamoorthy, Mohamed Hamed, Amr F Barakat, Nitin Kulkarni, Houman Khalili, Santiago Garcia and 3 more

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ramez MorcosDivision of Cardiology, Florida Atlantic University, Boca Raton, FL, USA.ORCID http://orcid.org/0000-0002-7234-6364
Haider Al TaiiHeart Rhythm Institute, University of Oklahoma Health Sciences Center, 800 Stanton L Young Blvd, Suite 5400, Oklahoma City, OK, 73104, USA.
Muni RubensBaptist Health South Florida, Miami, FL, USA.
Anshul SaxenaBaptist Health South Florida, Miami, FL, USA.
Venkataraghavan RamamoorthyBaptist Health South Florida, Miami, FL, USA.
Mohamed HamedDivision of Cardiology, Florida Atlantic University, Boca Raton, FL, USA.
Amr F BarakatHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Nitin KulkarniDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Houman KhaliliDivision of Cardiology, Florida Atlantic University, Boca Raton, FL, USA.
Santiago GarciaThe Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, OH, USA.
Michael MegalyWillis-Knighton Medical Center, Bossier City, LA, USA.
Emir VeledarBaptist Health South Florida, Miami, FL, USA.
Stavros StavrakisHeart Rhythm Institute, University of Oklahoma Health Sciences Center, 800 Stanton L Young Blvd, Suite 5400, Oklahoma City, OK, 73104, USA. Stavros-stavrakis@ouhsc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation (CA) and left atrial appendage closure (LAAC) require transseptal access; combining both in a single procedure may have advantages. However, the safety of this approach has not been extensively studied. The objective of this study was to compare in hospital outcomes among patients receiving CA, LAAC, and combination of both treatments on the same day.

methodsWe conducted a retrospective cohort analysis of the National Inpatient Sample database. The primary outcome was the presence of major adverse cardiovascular and cerebrovascular events (MACCE) during index hospitalization. Secondary outcomes included stroke, pericardial effusion, pericardiocentesis, and bleeding.

resultsA total of 69,285 hospitalizations with AF were included in the analysis, of which 71.7% received LAAC, 27.8% received CA, and 0.5% received combination of both treatments on the same day. MACEE (OR, 1.63; 95% CI, 0.39-6.70), stroke (OR, 2.98; 95% CI, 0.55-16.01), pericardial effusion (OR, 0.33; 95% CI, 0.07-1.41), pericardiocentesis (OR, 1.00; 95% CI, 0.25-3.86), and bleeding (OR, 3.25; 95% CI, 0.87-12.07) did not differ significantly between CA and combination treatment. Similarly, MACCE (OR, 1.11; 95% CI, 0.28-4.41), stroke (OR, 1.03; 95% CI, 0.24-4.35), pericardial effusion (OR, 0.45; 95% CI, 0.11-1.90), pericardiocentesis (OR, 0.63; 95% CI, 0.14-2.83), and bleeding (OR, 2.04; 95% CI, 0.65-6.39) did not differ significantly between LAAC and combination treatment.

conclusionsThe combined approach is infrequently used in clinical practice (< 1%). However, major life-threatening adverse events did not differ between CA and LAAC when performed in isolation or combined in a single procedural stage on the same day.

Indexed as

Atrial AppendageAtrial FibrillationCatheter AblationPericardial EffusionStrokeHemorrhageHospitalsHumansRetrospective StudiesTreatment OutcomeAtrial fibrillationCatheter ablationLeft atrial appendage

Identifiers

PMID36114936

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.