Evidence map›Paper›PMID 36114882›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2022

Preliminary results of two novel devices for epiphysiodesis in the reduction of excessive predicted final height in tall stature.

Andrea Laufer, Gregor Toporowski, Georg Gosheger, Ava von der Heiden, Jan Duedal Rölfing, Adrien Frommer, Anna Rachbauer, Carina Antfang, Robert Rödl, Bjoern Vogt

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Long-term outcome (28-40 years) after correction of leg length discrepancy through permanent epiphysiodesis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Article
  3. Article
  4. What's new in pediatric lower limb reconstruction?Journal of children's orthopaedics · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Andrea Laufer *Children's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0001-5658-2298
Gregor Toporowski *Children's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0001-8428-6031
Georg GoshegerGeneral Orthopaedics and Tumour Orthopaedics, University Hospital of Muenster, Muenster, Germany.ORCID http://orcid.org/0000-0003-1089-9972
Ava von der HeidenChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.
Jan Duedal RölfingChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0001-7934-2983
Adrien FrommerChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0003-1043-5895
Anna RachbauerChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0003-0279-488X
Carina AntfangChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0003-0096-8444
Robert RödlChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0002-1731-6293
Bjoern VogtChildren's Orthopaedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany. bjoern.vogt@ukmuenster.de.ORCID http://orcid.org/0000-0002-8781-2751
University Hospital Münster · DEAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the treatment of tall stature, the reduction of excessive predicted final height can either be achieved by hormonal treatment or surgically by temporary (tED) or permanent (pED) epiphysiodesis. The present study evaluates the preliminary results of two novel devices for tED and pED around the knee to reduce the predicted final height. MATERIALS AND

methodsA retrospective analysis was performed to evaluate the clinical and radiographic outcome after bilateral epiphysiodesis for the treatment of tall stature. A cohort of 34 patients (16 girls, 18 boys) who underwent either tED or pED between 2015 and 2020 were eligible for analysis based on the electronic patient records and picture archiving and communication system of our orthopaedic teaching hospital. tED was conducted in 11 patients (32%) through bilateral implantation of four RigidTacks™ (Merete, Berlin, Germany) around the knee. Twenty-three patients (68%) received pED, performed with an EpiStop™ trephine (Eberle, Wurmberg, Germany). The mean overall follow-up time was 2.9 years.

resultsThe mean age at surgery was 12.3 years in girls and 13.2 years in boys. Patients had a mean body height of 175.2 cm in girls and 184.7 cm in boys at surgery. The mean predicted final height was 191.4 cm in girls and 210.4 cm in boys. At the last follow-up, 26 patients (76.5%) had achieved skeletal maturity. The mean height of skeletally mature patients was 187.2 cm in girls and 198.5 cm in boys. A mean reduction of the predicted final height of 5.9 cm in girls and 8.7 cm in boys was achieved, corresponding to a reduction in remaining growth of 46% in girls and 38% in boys. Secondary frontal plane deformities of the knee were detected in 5/11 patients (45.5%) in the tED group and 1/23 treatments (4.3%) in the pED group.

conclusionstED and pED have both proven to be efficient at achieving growth inhibition to reduce excessive predicted height. However, tED has been associated with an increased risk of secondary angular deformities of the knee. Furthermore, the risk of implant-related complications and the necessity of a subsequent surgical intervention for implant removal have led our study group to abandon tED when treating tall stature. Long-term results of both procedures are pending. LEVEL OF EVIDENCE: 4:

Indexed as

Orthopedic ProceduresAdolescentBody HeightChildFemaleGrowth DisordersHumansMaleRetrospective StudiesAdolescentChildrenEpiStopGrowth arrestHeight reductionKneePermanent epiphysiodesisRigidTackTall statureTemporary epiphysiodesis

Identifiers

PMID36114882
PMCPMC9482560
OpenAlexW4296120360

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.