Evidence map›Paper›PMID 36114840›Full record

ArticleEuropean journal of applied physiology2022

The effect of prolonged interval and continuous exercise in the heat on circulatory markers of intestinal barrier integrity.

Zachary McKenna, Jonathan Houck, Jeremy Ducharme, Zidong Li, Quint Berkemeier, Zachary Fennel, Andrew Wells, Christine Mermier, Michael Deyhle, Orlando Laitano and 1 more

Erratum issuedAbstract read
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In one paragraph

Article in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Prebiotic BimunoExperimental physiology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Zachary McKennaDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA. zmckenna@unm.edu.ORCID http://orcid.org/0000-0003-2502-8870
Jonathan HouckDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Jeremy DucharmeDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Zidong LiDepartment of Molecular Biology and Chemistry, Christopher Newport University, Newport News, VA, USA.
Quint BerkemeierDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Zachary FennelDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Andrew WellsDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Christine MermierDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Michael DeyhleDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Orlando LaitanoDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Fabiano AmorimDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to determine the effect of prolonged high-intensity interval (INT) and moderate-intensity continuous (CONT) treadmill exercise in the heat on markers of enterocyte injury and bacterial endotoxin translocation.

methodsNine males completed 2 h of work-matched exercise in the heat (40 °C and 15% RH) as either INT (2 min at 80% VO

resultsI-FABP was significantly increased from pre- to post-exercise in CONT (913.96 ± 625.13 to 1477.26 ± 760.99 pg•mL

conclusionsWe conclude that prolonged exercise in the heat induces enterocyte injury, but interval (or intermittent) exercise may cause greater bacterial endotoxin translocation which may increase the risk for local and systemic inflammation.

Indexed as

ExerciseHot TemperatureBiomarkersEndotoxinsExercise TestHumansIntestinesMaleBiomarkersEndotoxinsExertional heat strokeGastrointestinal permeabilityHeat stress

Identifiers

PMID36114840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.