Evidence map›Paper›PMID 36114782›Full record

ArticleJournal of clinical laboratory analysis2022

The inflammatory cellular feature in the peripheral blood of chronic subdural hematoma patients.

Yibing Fan, Di Wu, Xinjie Zhang, Weiwei Jiang, Meng Nie, Xuanhui Liu, Tangtang Xiang, Mingqi Liu, Yupeng Chen, Dongyi Feng and 3 more

Abstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yibing FanDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0003-2944-4505
Di WuDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Xinjie ZhangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Weiwei JiangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Meng NieDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Xuanhui LiuDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Tangtang XiangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Mingqi LiuDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Yupeng ChenDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Dongyi FengDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Jinhao HuangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Chuang GaoDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Rongcai JiangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0002-9119-0115

Funding

National Natural Science Foundation of China 81671221National Natural Science Foundation of China 82001323National Natural Science Foundation of China 82071390Tianjin Research Program of Application Foundation and Advanced Technology 19YFZCSY00650
6 · The paper itself

Abstract

backgroundChronic subdural hematoma (CSDH) is a common neurosurgical disease with an increasing incidence. The absorption route of CSDH is not clear. Whether inflammatory factors enter the peripheral blood and cause systemic reactions is unknown.

methodsWe screened 105 CSDH patients and 105 control individuals. Their clinical characteristics and blood routine results were collected and compared. The blood routine changes of CSDH patients before and after treatment were compared. Age-stratified analysis was performed due to age may affect the inflammatory markers.

resultsThe white blood cell count, absolute neutrophil count, neutrophil percentage, neutrophil-lymphocyte count ratio (NLR), and platelet to lymphocyte count ratio (PLR) of CSDH patients before treatment were within the normal range, while were significantly higher than the control individuals (p < 0.001). The absolute lymphocyte count and lymphocyte percentage of control individuals were higher than those of patients (p < 0.001). The inflammatory cells in patients of different age groups were similar. After the patient was cured, the white blood cell count, the absolute value and percentage of neutrophils decreased (p < 0.05), while the number of monocytes increased.

conclusionsCSDH caused slight systemic inflammatory responses in the peripheral blood, implying that there is a non-hematologic route for the absorption of hematoma.

Indexed as

Hematoma, Subdural, ChronicHumansLeukocyte CountLymphocyte CountLymphocytesNeutrophilsRetrospective Studiesabsorption routeblood routine testchronic subdural hematomalocal inflammationsystemic inflammatory responses

Identifiers

PMID36114782
PMCPMC9551118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.