Evidence map›Paper›PMID 36114501›Full record

ArticleBMC health services research2022

Opportunities and considerations for the design of decentralized delivery of antiretroviral therapy for female sex workers living with HIV in South Africa.

Carly A Comins, Vijayanand Guddera, Lauren E Parmley, Katherine Young, Mfezi Mcingana, Ntambue Mulumba, Sharmistha Mishra, Deliwe R Phetlhu, Harry Hausler, Sheree Schwartz and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Carly A CominsDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, 21205, USA. ccomins1@jhu.edu.
Vijayanand GudderaTB HIV Care, Durban, South Africa.
Lauren E ParmleyUnited States Agency for International Development, Pretoria, South Africa.
Katherine YoungTB HIV Care, Cape Town, South Africa.
Mfezi McinganaTB HIV Care, Cape Town, South Africa.
Ntambue MulumbaTB HIV Care, Cape Town, South Africa.
Sharmistha MishraLi Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Deliwe R PhetlhuSchool of Health Care Sciences, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South Africa.
Harry HauslerTB HIV Care, Cape Town, South Africa.
Sheree SchwartzDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, USA.
Stefan BaralDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, USA.
Johns Hopkins University · USRight to Care · ZASefako Makgatho Health Sciences University · ZAUnited States Agency for International Development · USUniversity of Toronto · CA

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Examining PrEP use, implementation preferences and the potential for social support to improve PrEP delivery and persistence among female sex workers in Durban, South AfricaR01NR016650 · NINR · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2016 to 2020
$3.2M
Johns Hopkins University Center for AIDS Research through the National Institutes of Health P30AI094189National Institute of Nursing Research of the National Institutes of Health R01NR016650NIAID NIH HHS P30 AI094189NINR NIH HHS R01 NR016650
6 · The paper itself

Abstract

backgroundIn South Africa, 60% of female sex workers (FSW) are living with HIV, many of whom experience structural and individual barriers to antiretroviral therapy (ART) initiation and adherence. Community-based decentralized treatment provision (DTP) may mitigate these barriers. To characterize optimal implementation strategies, we explored preferences for DTP among FSW living with HIV in Durban, South Africa.

methodsThirty-nine semi-structured in-depth interviews were conducted with FSW living with HIV (n = 24), and key informants (n = 15) including HIV program implementers, security personnel, and brothel managers. Participants were recruited using maximum variation and snowball sampling. Interviews were conducted in English or isiZulu between September-November 2017 and analyzed using grounded theory in Atlas.ti 8.

resultsDTP was described as an intervention that could address barriers to ART adherence and retention, minimizing transport costs, time and wage loss from clinic visits, and act as a safety net to address FSW mobility and clinic access challenges. Respondents highlighted contextual considerations for DTP and suggested that DTP should be venue-based, scheduled during less busy times and days, and integrate comprehensive health services including psychological, reproductive, and non-communicable disease services. ART packaging and storage were important for community-based delivery, and participants suggested DTP should be implemented by sex work sensitized staff with discrete uniform and vehicle branding.

conclusionsIncorporating FSW preferences may support implementation optimization and requires balancing of tensions between preferences and feasibility. These data suggest the potential utility of DTP for FSW as a strategy to address those most marginalized from current ART programs in South Africa.

Indexed as

HIV InfectionsSex WorkersFemaleHealth ServicesHumansSex WorkSouth AfricaAntiretroviralDifferentiated careDifferentiated service deliveryFemale sex workersHIVSouth Africa

Identifiers

PMID36114501
PMCPMC9482230
OpenAlexW4295996330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.