Evidence map›Paper›PMID 36114471›Full record

ArticleBMC primary care2022

Drugs utilization profile in England and Wales in the past 15 years: a secular trend analysis.

Abdallah Y Naser, Hassan Alwafi, Tamara Al-Daghastani, Sara Ibrahim Hemmo, Hamzeh Mohammad Alrawashdeh, Zahraa Jalal, Vibhu Paudyal, Nawras Alyamani, Murouj Almaghrabi, Ahmad Shamieh

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In one paragraph

Article in BMC primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Abdallah Y NaserDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, Jordan. abdallah.naser@iu.edu.jo.
Hassan AlwafiFaculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia.
Tamara Al-DaghastaniDepartment of Medical Allied Sciences, Al-Balqa Applied University, Al-Salt, Jordan.
Sara Ibrahim HemmoDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, Jordan.
Hamzeh Mohammad AlrawashdehDepartment of Ophthalmology, Sharif Eye Centers, Irbid, Jordan.
Zahraa JalalSchool of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.
Vibhu PaudyalSchool of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.
Nawras AlyamaniFaculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia.
Murouj AlmaghrabiFaculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia.
Ahmad ShamiehDaniel Castro Dental Clinics, El Paso, TX, USA.
Umm al-Qura University · SAIsra University · JOUniversity of Birmingham · GBAl-Balqa Applied University · JOMédecins Sans Frontières · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication use assessment has a critical role in promoting the effective and rational use of pharmaceutical medications. There are no studies that have explored the utilization of all medications in England and Wales in the past 15 years without restrictions in the age group being studied or class of medications.

aimTo explore the medication utilization pattern of dispensed medications in England and Wales in the past 15 years.

methodA secular trend analysis study using publically available dispensing data on the population level in England and Wales for the duration between 2004 and 2019. Medication dispensing data was extracted from the Prescription Cost Analysis database.

resultsMedication prescriptions rate increased by 42.6% [from 1,345,095.75 (95% CI 1,345,004.25 - 1,345,187.26) in 2004 to 1,918,138.48 (95% CI 1,918,038.38 - 1,918,238.57) in 2019 per 100,000 persons, trend test, p < 0.001]. During the study period, the most common medication prescriptions were for the cardiovascular system, central nervous system, and endocrine system, which accounted for 30.2%, 18.8%, and 9.4%, respectively. The rate of medication prescriptions for skin, immunological products and vaccines, infections, and musculoskeletal and joint diseases decreased by 18.4%, 15.8%, 9.8%, and 5.7%, respectively.

conclusionThe last two decades have witnessed a remarkable rise in the quantity of medications dispensed in community settings. Utilization of chronic disease medications has increased in the past 15 years, specifically, dispensed medications for the cardiovascular system, central nervous system, and endocrine system. It is necessary to conduct additional cohort studies to investigate the clinical outcomes and prescribing safety of these medications.

Indexed as

Drug PrescriptionsDrug UtilizationCohort StudiesEnglandHumansPharmaceutical PreparationsWalesPharmaceutical PreparationsDrugs utilizationEnglandMedicationsUnited KingdomWales

Identifiers

PMID36114471
PMCPMC9482186
OpenAlexW4296162081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.