Evidence map›Paper›PMID 36114449›Full record

ArticleBMC microbiology2022

Quantitative and qualitative characterization of commercially available oral suspension of probiotic products containing Bacillus Clausii spores.

Akash Kharwar, Mohd Rabi Bazaz, Manoj P Dandekar

Abstract read
In one paragraph

Article in BMC microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Probiotic properties ofFrontiers in microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The Resistance Abilities of SomeFood science & nutrition · 2025
    Article
  9. Probiotic Spores ofInternational journal of molecular sciences · 2025
    Article
  10. Frontiers in microbiology · 2025
    Article
  11. Review
  12. Review
  13. Characterization ofScience progress
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Akash KharwarDepartment of Biological Sciences, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Telangana, 500037, India.
Mohd Rabi BazazDepartment of Biological Sciences, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Telangana, 500037, India.
Manoj P DandekarDepartment of Biological Sciences, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Telangana, 500037, India. manoj.dandekar@niperhyd.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics contain beneficial live bacteria that confer several health benefits to the host. For the past 50 years, spore-forming Bacillus species have been used in the form of probiotics. Among these, Bacillus clausii strains are used for the management of acute and antibiotic-associated diarrhoea. In the present work, we have evaluated the asserted label information on randomly chosen commercial Bacillus clausii spore suspension of probiotic products. The quality and number of viable bacteria were evaluated based on the colony count, antibiotic resistance, and hemolytic activity assays. The colony fingerprinting and 16S rRNA gene-sequencing techniques were used to confirm the presence of a univariate strain (Bacillus clausii). Our results corroborated the label count of 2 × 10

Indexed as

BacillusBacillus clausiiProbioticsAnti-Bacterial AgentsRNA, Ribosomal, 16SSpores, BacterialAnti-Bacterial AgentsRNA, Ribosomal, 16SAntibiotic resistanceBacillus clausiiDiarrhoeaProbioticsSpore count

Identifiers

PMID36114449
PMCPMC9482283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.