Evidence map›Paper›PMID 36114396›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2022

Shifting the Goalpost in Ventral Hernia Care: 5-year Outcomes after Ventral Hernia Repair with Poly-4-hydroxybutyrate Mesh.

Ankoor A Talwar, Nikhita J Perry, Phoebe B McAuliffe, Abhishek A Desai, Sheri Thrippleton, Robyn B Broach, John P Fischer

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ankoor A TalwarDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA.ORCID 0000-0003-0912-458X
Nikhita J PerryDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA.
Phoebe B McAuliffeDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA.
Abhishek A DesaiDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA.
Sheri ThrippletonDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA.
Robyn B BroachDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA.
John P FischerDivision of Plastic Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 14th Floor South Tower, Philadelphia, PA, 19104, USA. John.Fischer2@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVentral hernia repair (VHR) can be augmented with biosynthetic poly-4-hydroxybutryate mesh (P4HB). Long-term outcomes, including quality of life outcomes, after VHR with P4HB mesh are not well established. Our study sought to assess these outcomes 5 years after repair.

methodsPatients who received VHR using P4HB by the senior author between 01/2015 and 09/2017 were retrospectively identified. Patients were prospectively interviewed for quality of life assessment using the Hernia-Related Quality-of-Life Survey (HerQLes) and Abdominal Hernia-Q (AHQ) and screened for recurrence. Those who screened positive were asked to follow up in clinic to confirm recurrence. Both 5-year quality of life and recurrence were univariately assessed with patient and operative factors.

results51 patients met inclusion criteria. 43 patients completed 5-year quality of life assessment (84.3% response rate). Quality of life scores at all postoperative time periods were greater than preoperative scores. Further, quality of life at 5 years is greater than that assessed 0-2 years following VHR. Most patients achieve their best quality of life in the 5-year time period. Thirty-five patients had clinical follow-up in the 5-year time period, 7 experienced recurrences (20% recurrence rate). There was no difference in 5-year quality of life assessment between those who had a recurrence and those who did not.

conclusionPatient quality of life following VHR with P4HB improves immediately and continues to improve 5 years following repair. There are no differences in quality of life with onset of recurrence. Quality of life should be the primary outcome of success in VHR.

Indexed as

Hernia, VentralHerniorrhaphyHumansHydroxybutyratesQuality of LifeRecurrenceRetrospective StudiesSurgical MeshTreatment OutcomeHydroxybutyratesFive-yearHerniaPhasixPoly-4-hydroxybutyrateQuality of lifeVentral

Identifiers

PMID36114396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.