Evidence map›Paper›PMID 36114385›Full record

Trial reportInfection2023

Diagnostic nomogram to differentiate between epididymal tuberculosis and bacterial epididymitis.

Pengju Liu, Guofeng Cai, Hai Gu, Yong Qin

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pengju LiuDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Guofeng CaiDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Hai GuDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Yong QinDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China. hhyyqinyong@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe developed and validated a diagnostic nomogram for differentiating epididymal tuberculosis (TB) from bacterial epididymitis.

methodsIn this retrospective study, we developed a prediction model based on demographics and clinical characteristics. Eligible patients were randomly divided into derivation and validation cohorts (ratio 7:3). Univariate and multivariate regression analyses were used to filter variables and select predictors. Multivariate logistic regression was used to construct the nomogram. Concordance index (C-index), calibration plots, and decision curves analysis (DCA) were used to assess the discrimination, calibration, and clinical usefulness of the nomogram.

resultsWe included 147 patients (epididymal TB, 93; bacterial epididymitis, 54). The derivation cohort included 66 patients with epididymal TB and 38 with bacterial epididymitis; the validation cohort included 27 patients with epididymal TB and 16 with bacterial epididymitis. One regression model was built from three differential variables: body mass index, purified protein derivative, and chronic infection. Accordingly, one nomogram was developed. The model had good discrimination and calibration. C-indexes of the derivation and validation cohorts were 0.89 and 0.98 (95% confidence intervals, 0.83-0.95 and 0.94-1.01), respectively. DCA showed that the proposed nomogram was useful for differentiation.

conclusionThe nomogram can differentiate between epididymal TB and bacterial epididymitis.

Indexed as

EpididymitisTuberculosisBody Mass IndexHumansMaleNomogramsRetrospective StudiesBacterial epididymitisBody mass indexChronic infectionDiagnostic nomogramEpididymal tuberculosisPurified protein derivative

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.