Evidence map›Paper›PMID 36113122›Full record

ArticleAutism : the international journal of research and practice2022

Exposure to family stressful life events in autistic children: Longitudinal associations with mental health and the moderating role of cognitive flexibility.

Virginia Carter Leno, Nicola Wright, Andrew Pickles, Rachael Bedford, Anat Zaidman-Zait, Connor Kerns, Pat Mirenda, Lonnie Zwaigenbaum, Eric Duku, Teresa Bennett and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Measuring flexibility in autistic adults: Exploring the factor structure of the flexibility scale self report.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Virginia Carter LenoKing's College London, UK.ORCID 0000-0002-7455-5514
Nicola WrightKing's College London, UK.
Andrew PicklesKing's College London, UK.
Rachael BedfordKing's College London, UK.
Anat Zaidman-ZaitTel Aviv University, Israel.ORCID 0000-0002-2336-5147
Connor KernsThe University of British Columbia, Canada.ORCID 0000-0003-0832-8329
Pat MirendaThe University of British Columbia, Canada.ORCID 0000-0002-1016-3589
Lonnie ZwaigenbaumUniversity of Alberta, Canada.
Eric DukuOfford Centre for Child Studies, Canada.
Teresa BennettOfford Centre for Child Studies, Canada.
Stelios GeorgiadesOfford Centre for Child Studies, Canada.
Isabel SmithDalhousie University, Canada.ORCID 0000-0001-5525-2123
Tracy VaillancourtUniversity of Ottawa, Canada.
Peter SzatmariUniversity of Toronto, Canada.
Mayada ElsabbaghMcGill University, Canada.
King's College London · GBMcMaster University · CAUniversity of British Columbia · CADalhousie University · CAMcGill University · CAUniversity of Alberta · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

CIHRDepartment of Health NF-SI-0617-10120Wellcome TrustWellcome Trust 213608/Z/18/Z
6 · The paper itself

Abstract

lay abstractExperiencing stressful life events, such as a parent having had serious illness, parental divorce, bullying and victimization, is known to increase risk for mental health difficulties in neurotypical children. However, few studies have looked at whether stressful life events have a similar impact in autistic youth and if any individual characteristics may moderate the impact of said life events. In this study, we tested whether in autistic children aged 7-11 years, exposure to family-level stressful life events predicted later mental health symptoms (and vice versa). We also tested whether associations between stressful life events and mental health symptoms differed depending on the child's level of cognitive flexibility. We found stressful life events only predicted internalizing symptoms (such as anxiety and depression) in children with clinically significant difficulties in cognitive flexibility (as rated by their parents). Mental health symptoms did not predict future exposure to stressful life events. Results suggest that information about exposure to stressful life events and cognitive inflexibility may be helpful in identifying autistic children who may be at risk of developing anxiety and depression symptoms.

Indexed as

Autism Spectrum DisorderAutistic DisorderAdolescentAnxietyChildCognitionHumansLife Change EventsMental Healthautism spectrum disordercognitive flexibilityexecutive functioningmental healthstressful life events

Identifiers

PMID36113122
PMCPMC9483693
OpenAlexW4206631185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.