Evidence map›Paper›PMID 36113115›Full record

ArticleACS chemical neuroscience2022

Impaired Dopamine Release and Latent Learning in Alzheimer's Disease Model Zebrafish.

Romana Jarosova, Sayuri S Niyangoda, Piyanka Hettiarachchi, Michael A Johnson

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Quantitative Control of ZnAnalytical chemistry · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Romana JarosovaDepartment of Chemistry and R.N. Adams Institute for Bioanalytical Chemistry, University of Kansas, Lawrence, Kansas 66045, United States.ORCID 0000-0002-0529-8294
Sayuri S NiyangodaDepartment of Chemistry and R.N. Adams Institute for Bioanalytical Chemistry, University of Kansas, Lawrence, Kansas 66045, United States.
Piyanka HettiarachchiDepartment of Chemistry and R.N. Adams Institute for Bioanalytical Chemistry, University of Kansas, Lawrence, Kansas 66045, United States.
Michael A JohnsonDepartment of Chemistry and R.N. Adams Institute for Bioanalytical Chemistry, University of Kansas, Lawrence, Kansas 66045, United States.ORCID 0000-0001-5078-9896
University of Kansas · US

Funding

Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LUNTE, SUSAN M · 2012 to 2021
$22.1M
Synthetic Chemical Biology CoreP30GM145499 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI Susan M Lunte · 2022 to 2026
$6.9M
Tools for neuronal pathway analysis at sub-second and single-cell resolutionR21NS109659 · NINDS · UNIVERSITY OF KANSAS LAWRENCE · PI JOHNSON, MICHAEL A. · 2018 to 2019
$406k
NIGMS NIH HHS P20 GM103638NIGMS NIH HHS P30 GM145499NINDS NIH HHS R21 NS109659
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive, fatal, neurodegenerative disorder for which only treatments of limited efficacy are available. Despite early mentions of dementia in the ancient literature and the first patient diagnosed in 1906, the underlying causes of AD are not well understood. This study examined the possible role of dopamine, a neurotransmitter that is involved in cognitive and motor function, in AD. We treated adult zebrafish (

Indexed as

Alzheimer DiseaseDopamineAnimalsCarbon FiberMicroelectrodesNeurotransmitter AgentsOkadaic AcidZebrafishCarbon FiberDopamineNeurotransmitter AgentsOkadaic AcidAlzheimer’s diseasebehaviordopaminefast-scan cyclic voltammetryokadaic acidzebrafish

Identifiers

PMID36113115
PMCPMC10127145
OpenAlexW4295997630

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.