Evidence map›Paper›PMID 36112830›Full record

ArticleJournal of primary care & community health

The Direct to Consumer Stem Cell Market and the Role of Primary Care Providers in Correcting Misinformation.

Jennifer R Arthurs, Charlene M Martin Lillie, Zubin Master, Shane A Shapiro

Open access · goldAbstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jennifer R ArthursMayo Clinic, Jacksonville, FL, USA.ORCID 0000-0001-9691-4365
Charlene M Martin LillieMayo Clinic, Rochester, MN, USA.
Zubin MasterMayo Clinic, Rochester, MN, USA.
Shane A ShapiroMayo Clinic, Jacksonville, FL, USA.
Mayo Clinic in Arizona · USWinnMed · US

Funding

Designing Effective Health Education for Patients Seeking Unregulated Stem Cell InterventionsR21AG068620 · NIA · MAYO CLINIC ROCHESTER · PI MASTER, ZUBIN · 2021 to 2022
$437k
NIA NIH HHS R21 AG068620
6 · The paper itself

Abstract

introductionDirect to consumer stem cell and regenerative interventions (SCRIs) for various medical conditions have increased in popularity due to unmet medical needs and the promise of SCRIs to meet those needs. These interventions may have varying levels of safety and efficacy data and many lack sufficient scientific data to be marketed. The direct to consumer SCRI industry has received significant attention due to potential physical, economic, and emotional harms to patients. Patients may seek the counsel of their primary care providers when considering stem cell therapy for their condition.

methodsHere we describe strategies primary care providers can utilize when counseling patients.

resultsAlthough we recommend constructing these discussions around individual patients' needs, one can utilize a general approach consisting of 4 parts. First, providers should recognize what information the patient is seeking and what is their understanding of stem cell and regenerative medicine. Next, providers should convey evidence-based information at the level of patients understanding so that they are aware of the risks, benefits, and descriptions of possible procedures. Throughout the conversations, attempts should be made to guide patients to a trusted resource that can provide additional information. Finally, providers should make an effort to address misinformation in a way that is nonjudgmental and patient-centered to make the patient feel safe and comfortable.

conclusionEffectively communicating risk information by primary care providers to patients is important given the harms reported from direct-to-consumer SCRIs. Correcting misinformation remains a priority when discussing SCRI's. Providers should strive to offer patients with additional resources such as the opportunity for consultation with a specialist or a consultation service dedicated to informing patients about regenerative medicine.

Indexed as

CommunicationStem CellsHumansPrimary Health CareReferral and Consultationcommunity healthhealth literacymisinformationprimary careregenerative medicinestem cell

Identifiers

PMID36112830
PMCPMC9476238
OpenAlexW4295540245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.