Evidence map›Paper›PMID 36112718›Full record

ArticlePLoS neglected tropical diseases2022

COVID-19 in Africa: Underreporting, demographic effect, chaotic dynamics, and mitigation strategy impact.

Nathan Thenon, Marisa Peyre, Mireille Huc, Abdoulaye Touré, François Roger, Sylvain Mangiarotti

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. SARS-CoV-2 seroprevalence in vaccine-naïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathan ThenonCentre d'Etudes Spatiales de la Biosphère, CESBIO/OMP, UMR UPS-CNES-CNRS-IRD-INRAe, Toulouse, France.
Marisa PeyreAnimal Santé Territoires Risques Ecosystèmes, ASTRE/CIRAD, UMR CIRAD-INRAe-University of Montpellier, Montpellier, France.
Mireille HucCentre d'Etudes Spatiales de la Biosphère, CESBIO/OMP, UMR UPS-CNES-CNRS-IRD-INRAe, Toulouse, France.
Abdoulaye TouréCentre de Recherche et de Formation en Infectiologie de Guinée, Université Gamal Abdel Nasser de Conakry, Conakry, Guinea.
François RogerAnimal Santé Territoires Risques Ecosystèmes, ASTRE/CIRAD, UMR CIRAD-INRAe-University of Montpellier, Montpellier, France.
Sylvain MangiarottiCentre d'Etudes Spatiales de la Biosphère, CESBIO/OMP, UMR UPS-CNES-CNRS-IRD-INRAe, Toulouse, France.ORCID 0000-0002-5959-9770

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidemic of COVID-19 has shown different developments in Africa compared to the other continents. Three different approaches were used in this study to analyze this situation. In the first part, basic statistics were performed to estimate the contribution of the elderly people to the total numbers of cases and deaths in comparison to the other continents; Similarly, the health systems capacities were analysed to assess the level of underreporting. In the second part, differential equations were reconstructed from the epidemiological time series of cases and deaths (from the John Hopkins University) to analyse the dynamics of COVID-19 in seventeen countries. In the third part, the time evolution of the contact number was reconstructed since the beginning of the outbreak to investigate the effectiveness of the mitigation strategies. Results were compared to the Oxford stringency index and to the mobility indices of the Google Community Mobility Reports. Compared to Europe, the analyses show that the lower proportion of elderly people in Africa enables to explain the lower total numbers of cases and deaths by a factor of 5.1 on average (from 1.9 to 7.8). It corresponds to a genuine effect. Nevertheless, COVID-19 numbers are effectively largely underestimated in Africa by a factor of 8.5 on average (from 1.7 to 20. and more) due to the weakness of the health systems at country level. Geographically, the models obtained for the dynamics of cases and deaths reveal very diversified dynamics. The dynamics is chaotic in many contexts, including a situation of bistability rarely observed in dynamical systems. Finally, the contact number directly deduced from the epidemiological observations reveals an effective role of the mitigation strategies on the short term. On the long term, control measures have contributed to maintain the epidemic at a low level although the progressive release of the stringency did not produce a clear increase of the contact number. The arrival of the omicron variant is clearly detected and characterised by a quick increase of interpeople contact, for most of the African countries considered in the analysis.

Indexed as

COVID-19AfricaAgedDemographyHumansSARS-CoV-2

Identifiers

PMID36112718
PMCPMC9518880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.