ArticleScience advances2022
A flexible electronic strain sensor for the real-time monitoring of tumor regression.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Wearable Electronics for Precision Diagnosis Through Advanced Manufacturing and Integration.Nano-micro letters · 2026Review
- Advances and Challenges in Wearable Sensors for Health Monitoring.ACS applied materials & interfaces · 2026Review
- Implantable bioelectronic outlet.Science advances · 2026Article
- Liquid Metal-Enabled Soft Bioelectronics for Human Health Monitoring.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Ultrasensitive soft vibration sensors based on atomically thin metal dichalcogenide ribbon networks.Science advances · 2026Article
- Artificial intelligence-integrated wearable biomedical devices for cancer management.Journal of the National Cancer Center · 2025Review
- A highly sensitive and multiplexed wireless sensing system with skin-like compliance and stretchability for wearable applications.Science advances · 2025Article
- Wearable bioelectronics for cancer theranostics.Microsystems & nanoengineering · 2025Review
- A Piezoelectric Sensor Based on MWCNT-Enhanced Polyvinyl Chloride Gel for Contact Perception of Grippers.Biomimetics (Basel, Switzerland) · 2025Article
- Materials and device strategies to enhance spatiotemporal resolution in bioelectronics.Nature reviews. Materials · 2025Article
- A bio-inspired microwave wireless system for constituting passive and maintenance-free IoT networks.National science review · 2025Article
- MXene-MWCNT Conductive Network for Long-Lasting Wearable Strain Sensors with Gesture Recognition Capabilities.Micromachines · 2025Article
- Emerging Applications of EpCAM-Targeted Nuclear Medicine Probes: Current Research and Future Perspectives.International journal of nanomedicine · 2025Review
- Hypersensitive meta-crack strain sensor for real-time biomedical monitoring.Science advances · 2024Article
- Tumor Biomechanics-Inspired Future Medicine.Cancers · 2024Review
- A Simple Method to Manufacture a Force Sensor Array Based on a Single-Material 3D-Printed Piezoresistive Foam and Metal Coating.Sensors (Basel, Switzerland) · 2024Article
- Article
- Recent Advances in Wearable Healthcare Devices: From Material to Application.Bioengineering (Basel, Switzerland) · 2024Review
- Long-term monitoring of ultratrace nucleic acids using tetrahedral nanostructure-based NgAgo on wearable microneedles.Nature communications · 2024Article
- Advancements in Airborne Viral Nucleic Acid Detection with Wearable Devices.Advanced sensor research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Assessing the efficacy of cancer therapeutics in mouse models is a critical step in treatment development. However, low-resolution measurement tools and small sample sizes make determining drug efficacy in vivo a difficult and time-intensive task. Here, we present a commercially scalable wearable electronic strain sensor that automates the in vivo testing of cancer therapeutics by continuously monitoring the micrometer-scale progression or regression of subcutaneously implanted tumors at the minute time scale. In two in vivo cancer mouse models, our sensor discerned differences in tumor volume dynamics between drug- and vehicle-treated tumors within 5 hours following therapy initiation. These short-term regression measurements were validated through histology, and caliper and bioluminescence measurements taken over weeklong treatment periods demonstrated the correlation with longer-term treatment response. We anticipate that real-time tumor regression datasets could help expedite and automate the process of screening cancer therapies in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.