Evidence map›Paper›PMID 36112608›Full record

SynthesisEndocrinology, diabetes & metabolism2022

A systematic review: Cost-effectiveness of continuous glucose monitoring compared to self-monitoring of blood glucose in type 1 diabetes.

Yuxin Jiao, Rose Lin, Xinyang Hua, Leonid Churilov, Michele J Gaca, Steven James, Philip M Clarke, David O'Neal, Elif I Ekinci

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Endocrinology, diabetes & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Continuous glucose monitoring in type 2 diabetes: a systematic review of barriers and opportunities for care improvement.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025
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  13. Pediatric Type 1 Diabetes Care in Indonesia: A Review of Current Challenges and PracticeJournal of clinical research in pediatric endocrinology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yuxin JiaoAustin Health, Heidelberg, Victoria, Australia.ORCID 0000-0001-7580-3623
Rose LinAustin Health, Heidelberg, Victoria, Australia.
Xinyang HuaCentre for Health Policy, Melbourne School of Population and Global Health, University of Melbourne, Carlton, Victoria, Australia.
Leonid ChurilovMelbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.
Michele J GacaHealth Sciences Library, Austin Health, Heidelberg, Victoria, Australia.ORCID 0000-0001-7350-3299
Steven JamesSchool of Nursing, Midwifery and Paramedicine, University of the Sunshine Coast, Petrie, Queensland, Australia.ORCID 0000-0002-3928-9206
Philip M ClarkeHealth Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
David O'NealDepartment of Medicine, St Vincent's Hospital Melbourne, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.
Elif I EkinciDepartment of Medicine, Austin Health, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0003-2372-395X
The University of Melbourne · AUAustin Health · AUUniversity of Oxford · GBUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous glucose monitoring (CGM) is rapidly becoming a vital tool in the management of type 1 diabetes. Its use has been shown to improve glycaemic management and reduce the risk of hypoglycaemic events. The cost of CGM remains a barrier to its widespread application. We aimed to identify and synthesize evidence about the cost-effectiveness of utilizing CGM in patients with type 1 diabetes. Studies were identified from MEDLINE, Embase and Cochrane Library from January 2010 to February 2022. Those that assessed the cost-effectiveness of CGM compared to self-monitored blood glucose (SMBG) in patients with type 1 diabetes and reported lifetime incremental cost-effectiveness ratio (ICER) were included. Studies on critically ill or pregnant patients were excluded. Nineteen studies were identified. Most studies compared continuous subcutaneous insulin infusion and SMBG to a sensor-augmented pump (SAP). The estimated ICER range was [$18,734-$99,941] and the quality-adjusted life year (QALY) gain range was [0.76-2.99]. Use in patients with suboptimal management or greater hypoglycaemic risk revealed more homogenous results and lower ICERs. Limited studies assessed CGM in the context of multiple daily injections (MDI) (n = 4), MDI and SMBG versus SAP (n = 2) and three studies included hybrid closed-loop systems. Most studies (n = 17) concluded that CGM is a cost-effective tool. This systematic review suggests that CGM appears to be a cost-effective tool for individuals with type 1 diabetes. Cost-effectiveness is driven by reducing short- and long-term complications. Use in patients with suboptimal management or at risk of severe hypoglycaemia is most cost-effective.

Indexed as

Diabetes Mellitus, Type 1Blood GlucoseBlood Glucose Self-MonitoringCost-Benefit AnalysisFemaleHumansHypoglycemic AgentsBlood GlucoseHypoglycemic Agentscontinuous glucose monitoringcost-analysiscost-effectivenesshealth economicsself-monitoring blood glucosetype 1 diabetes

Identifiers

PMID36112608
PMCPMC9659662
OpenAlexW4296037362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.