ArticleInternal and emergency medicine2022
The association between albumin corrected anion gap and ICU mortality in acute kidney injury patients requiring continuous renal replacement therapy.
Article in Internal and emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dynamics of serum anion gaps with in-hospital mortality: Analysis of the multi-open databases.PloS one · 2024Pooled it
- Predictive Value of Anion Gap for Acute Kidney Injury Progression and Outcomes.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Anion gap trajectory patterns and prognosis in sepsis patients: A multicenter retrospective study.Medicine · 2026Article
- Association of ACAG with short-term mortality in liver failure patients: a retrospective analysis based on the MIMIC-IV database.Scientific reports · 2026Article
- Article
- Increased serum albumin corrected anion gap levels are associated with poor prognosis in sepsis-induced coagulopathy patients.PloS one · 2026Article
- Associations Between Albumin-Corrected Anion Gap and Mortality in Heart Failure Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Predictive Value of 48-hour Anion Gap Fluctuations in ICU Patients with Acute Kidney Injury: An Analysis based on MIMIC Database.Current pharmaceutical design · 2026Article
- Association Between Serum Anion Gap and Risk of Postoperative Delirium in Patients Undergoing Gastric Surgery in ICU: A Retrospective Study From the MIMIC-IV Database.Anesthesiology research and practice · 2026Article
- Association between albumin-corrected anion gap and 60-day all-cause mortality in critically ill shock patients.European journal of medical research · 2025Article
- Construction and evaluation of prediction model for renal function recovery in acute kidney injury patients undergoing continuous renal replacement therapy based on machine learning algorithms.Annals of medicine · 2025Article
- Group-based trajectory modeling of anion gap and mortality in patients with sepsis: a retrospective analysis of the MIMIC-IV database.European journal of medical research · 2025Article
- Non-linear association between anion gap and 28-day mortality in critically ill patients with COVID-19: a cohort study from MIMIC IV database.Journal of thoracic disease · 2025Article
- Association Between Albumin Corrected Anion Gap and 28-Day All-Cause Mortality in Patients With Acute Respiratory Failure in ICU: A Retrospective Study Based on the MIMIC-IV Database.The clinical respiratory journal · 2025Article
- Association between serum anion gap and all-cause mortality in critically ill patients with Gastrointestinal bleeding: insights from MIMIC-IV database.Scientific reports · 2025Article
- Serum albumin corrected anion gap levels are associated with poor prognosis in patients with acute ischemic stroke.Scientific reports · 2025Article
- The association of albumin-corrected anion gap and acute kidney injury in heart failure patients: a competing risk model analysis.BMC cardiovascular disorders · 2025Article
- The association between anion gap and prognosis in patients myocardial infarction with congestive heart failure: a retrospective analysis of the MIMIC-IV database.International journal of emergency medicine · 2025Article
- Association of elevated albumin-corrected anion gap with all-cause mortality risk in atrial fibrillation: a retrospective study.BMC cardiovascular disorders · 2025Article
- Albumin corrected anion gap and clinical outcomes in elderly patients with acute kidney injury caused or accompanied by sepsis: a MIMIC-IV retrospective study.European journal of medical research · 2025Article
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Abstract
The relationship between albumin corrected anion gap (ACAG) and mortality in acute kidney injury (AKI) patients who received continuous renal replacement therapy (CRRT) has not been investigated in any previous studies. This study aimed to investigate the relationship between ACAG at CRRT initiation and all-cause mortality among these patients in the intensive care unit (ICU). Patients diagnosed with AKI and treated with CRRT in the ICU from the Medical Information Mart for Intensive Care-IV version 1.0 (MIMIC IV) database and Huzhou Central Hospital were retrospectively enrolled. Participants were divided into two groups: the normal ACAG group (12-20 mmol/L) and high ACAG group (> 20 mmol/L). The Kaplan-Meier method and log-rank test were used to compare the survival rate between the two groups. Restricted cubic spine (RCS) and Cox proportional-hazards models were utilized to analyze the relationship between ACAG at CRRT initiation and ICU all-cause mortality of these patients. A total of 708 patients met the inclusion criteria in the study. The all-cause mortality of these patients during ICU hospitalization was 41.95%. Patients in the high ACAG group exhibited significantly higher ICU all-cause mortality rate than patients in the normal ACAG group (all P < 0.001). The Kaplan-Meier survival curves showed that the normal ACAG group had a higher ICU cumulative survival rate than the high ACAG group (log-rank test, χ
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